Results 221 to 230 of about 709,386 (365)

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

open access: yesMolecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur   +3 more
wiley   +1 more source

Extracellular vesicles  produced by bone marrow mesenchymal stem cells overexpressing programmed death‐ligand 1 ameliorate dextran sodium sulfate‐induced ulcerative colitis in rats by regulating Th17/Treg cell balance through PTEN/PI3K/AKT/mTOR axis

open access: yesJournal of Gastroenterology and Hepatology, Volume 37, Issue 12, Page 2243-2254, December 2022., 2022
Abstract Background and Aim Programmed death‐ligand 1 (PD‐L1) was involved in regulating Th17/Treg cell balance in ulcerative colitis (UC). Extracellular vesicles (EVs) from genetically modified bone marrow mesenchymal stem cells (BMSCs) can serve as a stable delivery system to overexpress PD‐L1.
Hongxia He   +8 more
wiley   +1 more source

Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor‐infiltrating lymphocytes, tumor‐draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer

open access: green, 2010
Takanori Maruyama   +7 more
openalex   +2 more sources

T-lymphocyte tyrosine hydroxylase regulates TH17 T-lymphocytes during repeated social defeat stress

open access: hybrid, 2022
Safwan Elkhatib   +3 more
openalex   +1 more source

Maslinic Acid Ameliorates DSS‐Induced Experimental Colitis by Suppressing Th Cell‐Mediated Inflammation via AICD Induction

open access: yesPhytotherapy Research, EarlyView.
This study suggests that maslinic acid treatment protected intestinal mucosa and ameliorated gut inflammation, accompanied with significantly reduced inflammatory cytokines and Th cell infiltration and subset differentiation. In vitro, maslinic acid suppressed Th cell proliferation and differentiation, regulated cell cycle distribution, and decreased ...
Dan Li   +8 more
wiley   +1 more source

Hetrombopag: A promising thrombopoietin receptor agonist for the treatment of primary and secondary immune thrombocytopenia

open access: yesRheumatology &Autoimmunity, EarlyView.
This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu   +8 more
wiley   +1 more source

Immunocto: a massive immune cell database auto-generated for histopathology [PDF]

open access: yesarXiv
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to characterising the TIME may be through combining (1) digitised microscopic high-resolution optical images of hematoxylin
arxiv  

Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

open access: yesCell Stem Cell, 2018
Annika Sommer   +15 more
semanticscholar   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Melatonin in Th17/Treg differentiation: the contribution of the hormone's own production by T lymphocytes

open access: diamond, 2023
Н. С. Глебездина   +2 more
openalex   +2 more sources

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