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Autoimmune thyroid diseases and Th17/Treg lymphocytes

Life Sciences, 2018
Years of researches have demonstrated that the imbalance of Th17 and Tregs contribute to the thyroid autoimmunity and the severity of autoimmune thyroid disease (AITD). The underlying mechanism comprises inherent genetic predisposition, abnormality of Th17 and Treg related biological molecules, and gut microbiota disorder.
Shiying, Shao, Xuefeng, Yu, Liya, Shen
openaire   +2 more sources

Activation of Peripheral Th17 Lymphocytes in Patients with Asthma

Immunological Investigations, 2009
A recently identified interleukin (IL)-17-producing T-helper (Th) lymphocyte subset, which comprises Th17 cells producing hallmark cytokines IL-17A, IL-17F and IL-22, is involved in chronic inflammatory diseases. Elevated gene and protein expressions of IL-17 are manifested in allergic asthma.
C K, Wong   +7 more
openaire   +2 more sources

Th17 and Th1 Lymphocytes Are Correlated with Chronic Periodontitis

Immunological Investigations, 2016
T cells are involved in the homeostasis of periodontal tissues and mediate bone loss in periodontitis, but the involvement of T-helper cells in chronic periodontitis (CP) in a Chinese population is still unclear. This study aimed to assess the distribution of peripheral and local T helper (Th17) and Th1 in CP.
Xiao-Tao, Chen   +5 more
openaire   +2 more sources

Les lymphocytes T régulateurs et les lymphocytes Th17 : fonctions physiologiques et pathologiques

Revue Francophone des Laboratoires, 2010
Resume Depuis maintenant deux decennies, les lymphocytes T CD4+ sont classes en differents sous-types en fonction des cytokines qu’ils secretent et de leurs fonctions dans la reponse immunitaire. Cette classification, longtemps cantonnee a deux sous-types de lymphocytes T auxiliaires ou « helper » appeles Th1 et Th2, a recemment ete incrementee de ...
Murielle Corvaisier-Chiron   +1 more
openaire   +1 more source

Le lymphocyte TH17 dernier-né de la famille des lymphocytes T CD4+

Pathologie Biologie, 2010
In recent years the T CD4+ lymphocyte family has grown. In the initial two components TH1 and TH2 lymphocytes were added the TH17 lymphocyte and T cell regulator (Treg). Under the influence of transforming growth factor β, interleukin 6 (IL6), IL21 and IL23, the naive lymphocyte T CD4+ differentiates in TH17.
M. Essakalli   +5 more
openaire   +1 more source

Factors of Th17 and Treg Lymphocyte Differentiation in Pulmonary Tuberculosis

Bulletin of Experimental Biology and Medicine, 2015
In patients with infiltrative pulmonary tuberculosis, the increase in IL-6 secretion, the decrease in TGFβ production (in case of drug resistance of the causative agent), and unchanged level of IL-1β secretion by mononuclear leukocytes in vitro were associated with increased number of CD4(+)CD161(+)IL-17A(+) Th17 lymphocytes in the peripheral blood. In
T E, Kononova   +5 more
openaire   +2 more sources

The role of Th17 lymphocytes in drug-resistant epilepsy

The Journal of Immunology, 2019
Abstract Epilepsy is a chronic neuronal disorder affecting ~65 millions people throughout the world. 1/3 of patients suffer from drug-resistant epilepsy (DRE). Objective to assess the relationship between different Th17 markers and the clinical course of epilepsy to uncover new ...
Oumarou Ouédraogo   +9 more
openaire   +1 more source

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