The Fos-related antigen 1–JUNB/activator protein 1 transcription complex, a downstream target of signal transducer and activator of transcription 3, induces T helper 17 differentiation and promotes experimental autoimmune arthritis [PDF]
, 2017 et al,, Kim, Woo Kyung
core +1 more source
Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets
ESC Heart Failure, Volume 12, Issue 3, Page 1739-1758, June 2025.Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley +1 more source
Changes in T Lymphocytes and Cytokines After Anti-TNF Treatment in Pediatric Inflammatory Bowel Disease: Association with Response to Pharmacologic Therapy. [PDF]
Int J Mol SciZapata-Cobo P +18 more
europepmc +1 more source
Bacterial Outer Membrane Vesicles: From Physics to Clinical
MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou +7 more
wiley +1 more source
The Role of IL-17A in Mediating Inflammatory Responses and Progression of Neurodegenerative Diseases. [PDF]
Int J Mol SciZheng MY, Luo LZ.
europepmc +1 more source
MedComm – Oncology, Volume 4, Issue 2, June 2025.Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen +11 more
wiley +1 more source
Oxidative Stress in Antigen Processing and Presentation
MedComm – Oncology, Volume 4, Issue 2, June 2025.Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang +9 more
wiley +1 more source
T helper cell 17/regulatory T cell balance regulates ulcerative colitis and the therapeutic role of natural plant components: a review. [PDF]
Front Med (Lausanne)Zhao D +11 more
europepmc +1 more source
A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer
The Journal of Pathology, Volume 266, Issue 2, Page 192-203, June 2025.Abstract Microsatellite instability is a strong predictor of response to immune checkpoint therapy and patient outcome in colorectal cancer. Although enrichment of distinct T‐cell subpopulations has been determined to impact the response to immune checkpoint therapy and patient outcome, little is known about the underlying changes in the composition of
Zhihao Huang +30 more
wiley +1 more source