Results 91 to 100 of about 152,627 (317)

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism

open access: yesAnnals of Neurology, EarlyView.
Objective Autophagy is a fundamental biological pathway with vital roles in intracellular homeostasis. During autophagy, defective cargoes including mitochondria are targeted to lysosomes for clearance and recycling. Recessive truncating variants in the autophagy gene EPG5 have been associated with Vici syndrome, a severe early‐onset neurodevelopmental
Hormos Salimi Dafsari   +140 more
wiley   +1 more source

Persisting Transglutaminase 6 Antibodies in Neurological Gluten‐Related Disorders

open access: yesAnnals of Neurology, EarlyView.
Objective Gluten‐related autoimmunity can cause neurological disease, although the best way to diagnose and monitor such patients is unclear. Serological testing for antibodies against transglutaminase 6 (TG6) has been proposed; however, this is not widely available in clinical practice.
Iain D. Croall   +6 more
wiley   +1 more source

Endogenous Repair in Vanishing White Matter

open access: yesAnnals of Neurology, EarlyView.
Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in the deep gray structures and brainstem.
Bonnie C. Plug   +7 more
wiley   +1 more source

Neurosyphilis with bilateral thalamic lesions as imaging manifestation: one case report

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
DOI:10.3969/j.issn.1672⁃6731.2020.11 ...
Jian HU   +4 more
doaj  

Amyloid Peptide Nanofibrils Promote Efficient Neurotransmitter Oxidation and Serve as Scaffolds for Melanin Production

open access: yesAngewandte Chemie, EarlyView.
Short amyloid peptides can act as efficient catalysts of neurotransmitter degradation, and libraries of short peptides can be used to identify core fragments present in larger proteins that might be linked to neurodegenerative diseases. Abstract We have shown that de novo designed peptides self‐assemble in the presence of copper to create ...
Inhye Kim   +5 more
wiley   +1 more source

Bioimaging of sense organs and the central nervous system in extant fishes and reptiles in situ: A review

open access: yesThe Anatomical Record, EarlyView.
Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin   +9 more
wiley   +1 more source

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