Results 151 to 160 of about 152,526 (259)

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Tremor pathophysiology. [PDF]

Clin Park Relat Disord
Elble RJ.
europepmc   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source

Real‐world outcomes of responsive neurostimulation in patients with Lennox–Gastaut syndrome: A multicenter retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types and high resistance to antiseizure medication (ASM), often necessitating nonpharmacologic therapies, including neuromodulation.
Shanna M. Swartwood, Robert J. Bollo, Catherine J. Chu, Alexandra L. Geffrey, Robert Mark Richardson, Hiroki Nariai, Aria Fallah, Samuel Ahn, Saadi Ghatan, Laura Chenevert, Maite La Vega‐Talbott, Audie C. Espinoza   +11 more
wiley   +1 more source

rTMS Suppresses Tobacco Craving via Enhanced Prefronto-Striato-Thalamic Connectivity. [PDF]

Addict Biol
Luo X, Ma X, Li S, Chen H, Yang B, Zheng Y, Dong GH.   +6 more
europepmc   +1 more source

Relative entropy as a biomarker for vagus nerve stimulation response in epilepsy: Insights from intracerebral electroencephalography

Epilepsia Open, EarlyView.
Abstract Objective This study aims to analyze differences in pre‐implantation invasive electroencephalographic (IEEG) data between vagus nerve stimulation (VNS) responders (>50% seizure reduction) and VNS nonresponders (<50% seizure reduction). Methods We retrospectively identified 19 patients with drug‐resistant focal epilepsy who underwent IEEG ...
Štěpán Erben, Jan Cimbálník, Eva Zatloukalová, Petra Búřilová, Jan Vinklárek, Barbora Sklenárová, Jan Chrastina, Eva Brichtová, Jitka Kočvarová, Ondřej Strýček, Martin Pail, Milan Brázdil, Irena Doležalová   +12 more
wiley   +1 more source

Thalamic homeostatic transcriptomic signatures are altered in a mouse model of cholestatic liver injury and are mitigated by systemic TNF neutralization. [PDF]

Mol Brain
Almishri W, Dunn JF, Swain MG.
europepmc   +1 more source

Fabrication of flexible composite electrodes and their application in flexible supercapacitors for wearable electronic devices

FlexMat, EarlyView.
This review surveys current progress in composite flexible electrodes for flexible supercapacitors, emphasizing how structural engineering and material synergy enhance both mechanical compliance and electrochemical performance. It discusses fabrication strategies, emerging application scenarios, and ongoing challenges, offering updated insights that ...
Weikang Wang, Qing Liu, Ang Lv, Shuai Zhou, Chunlei Zhang, Luping Zhang, Liming Li, Weiwei Zhao, Yuchun Tang, Fei Huang   +9 more
wiley   +1 more source

Implication of the thalamus in sleep alterations observed in Alzheimer's disease. [PDF]

Alzheimers Dement
Burnet-Merlin C, Hay YA, Brécier A.
europepmc   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source