Epilepsy surgery: From bench to the clinics
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley +1 more source
Alterations in self-related brain networks in autism spectrum disorder: a systematic review of functional and structural magnetic resonance imaging studies. [PDF]
Zhou L +5 more
europepmc +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren +12 more
wiley +1 more source
Morphological changes and lateralization of the thalamic nuclei in children with growth hormone deficiency. [PDF]
Lee JY +8 more
europepmc +1 more source
ILAE‐YES global webinar series: Integrating clinical and basic science in epilepsy research
An ILAE‐YES global webinar series bridging basic and clinical epilepsy research inspired new research ideas in 80% of participants. Abstract Summary Bridging clinical and basic research is increasingly recognized as a priority in the epilepsy field, yet opportunities for integration remain limited by the time, space, and financial constraints of ...
Cecilie G. Nome +22 more
wiley +1 more source
Appetite Perception and Cerebral Blood Flow in Aging Adults Following a Single Bout of Exercise. [PDF]
Malin SK +3 more
europepmc +1 more source
Postmortem MRI reveals distinct structural features in sudden unexpected death in epilepsy
Abstract Magnetic resonance imaging (MRI) abnormalities have been reported in individuals who later die from sudden unexpected death in epilepsy (SUDEP), but their specificity and predictive value remain uncertain. Postmortem MRI (PM‐MRI) offers a unique opportunity to distinguish structural features associated with SUDEP from changes related to ...
Andrea Hill +9 more
wiley +1 more source
Neurostructural alterations, trait impulsivity, and genetic architecture in individuals with methamphetamine dependence: a multimodal imaging-genetics study. [PDF]
Luo D +8 more
europepmc +1 more source
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston +6 more
wiley +1 more source

