Diffusion microstructure alterations in subcortical gray matter are associated with cognitive and motor performance in Parkinson's disease: a pilot study. [PDF]
Newman BT +9 more
europepmc +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Integrating Brain Morphological Features and Ionized Serum Magnesium to Identify Mild Tic Comorbidity in Children with Autism Spectrum Disorder. [PDF]
Chen X +9 more
europepmc +1 more source
Rest‐activity patterns across development in two mouse models of autism and epilepsy
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash +4 more
wiley +1 more source
Chorea-athetosis-like hyperkinetic seizures in temporal lobe epilepsy: insights from stereo-EEG in three patients. [PDF]
Zhuang J +7 more
europepmc +1 more source
Utility of repeat stereotactic EEG in pediatric patients with tuberous sclerosis
Abstract Objective Tuberous sclerosis complex (TSC) is a rare genetic disorder associated with early‐onset drug‐resistant epilepsy (DRE) secondary to intracranial tubers. Many patients undergo stereo‐EEG (sEEG) for seizure onset localization, sometimes requiring multiple sEEGs and subsequent epilepsy surgeries. Our objective was to evaluate the effects
Julie Uchitel +14 more
wiley +1 more source
Advances in neuroimaging studies of thalamic abnormalities in children with attention deficit hyperactivity disorder. [PDF]
Zhou J +12 more
europepmc +1 more source
Disrupted cerebellar networks in uncontrolled focal to bilateral tonic–clonic seizures
Abstract Objective Focal to bilateral tonic–clonic seizures (FBTC) are associated with significant morbidity and an elevated risk of sudden unexpected death in epilepsy (SUDEP). The cerebellum has been implicated in modulating the frequency and severity of tonic–clonic seizures.
John Phamnguyen +4 more
wiley +1 more source
Whole-brain input organization of <i>Kremen1</i>-positive striatal spiny projection neurons revealed by monosynaptic rabies tracing. [PDF]
Smith VMM +6 more
europepmc +1 more source
Auditory gamma‐band synchronization and attentional performance in juvenile myoclonic epilepsy
Abstract Objective Cognitive difficulties in juvenile myoclonic epilepsy (JME) are part of the clinical phenotype alongside epileptic seizures; however, the underlying neurophysiological mechanisms remain unclear. Auditory steady‐state responses (ASSRs) to repetitive 40‐ and 80‐Hz stimuli are widely used measures of gamma‐band oscillations (GBOs ...
Ryo Mitoma +12 more
wiley +1 more source

