Results 51 to 60 of about 255,451 (370)

Glial Activation in the Thalamus Contributes to Vestibulomotor Deficits Following Blast-Induced Neurotrauma

open access: yesFrontiers in Neurology, 2020
Vestibular impairment has become a frequent consequence following blast-related traumatic brain injury (bTBI) in military personnel and Veterans. Behavioral outcomes such as depression, fear and anxiety are also common comorbidities of bTBI.
Michelle R. Dickerson   +6 more
doaj   +1 more source

Neuroablative central lateral thalamotomy for chronic neuropathic pain

open access: yesFrontiers in Pain Research, 2022
Chronic neuropathic pain refractory to medical management can be debilitating and can seriously affect one's quality of life. The interest of ablative surgery for the treatment or palliation of chronic neuropathic pain, cancer-related or chemotherapy ...
Anthony K. Allam   +4 more
doaj   +1 more source

DeLTA-BIT: an open-source probabilistic tractography-based deep learning framework for thalamic targeting in functional neurological disorders [PDF]

open access: yesarXiv, 2023
In the last years there has been a growing interest in the applications of diffusion tractography for target identification in neurofunctional disorders for an increasingly tailored approach. The growing diffusion of well-established neurosurgical procedures as deep brain stimulation (DBS) and trans-cranial Magnetic Resonance-guided Focused Ultrasound (
arxiv  

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar   +6 more
wiley   +1 more source

Divergent outputs of the ventral lateral geniculate nucleus mediate visually evoked defensive behaviors

open access: yesCell Reports, 2021
Summary: Rapid alternations between exploration and defensive reactions require ongoing risk assessment. How visual cues and internal states flexibly modulate the selection of behaviors remains incompletely understood.
Lindsey D. Salay, Andrew D. Huberman
doaj  

Threshold Values of Sleep Spindles Features in Healthy Adults Using Scalp‐EEG and Associations With Sleep Parameters

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep spindles are an electrophysiological fingerprint of the sleeping human brain. They can be described in terms of duration, frequency, amplitude, and density, and vary widely according to age and sex. Spindles play a role in sleep and wake functions and are altered in several neurological and psychiatric disorders.
Julien Coelho   +8 more
wiley   +1 more source

What Happens When I Watch a Ballet and I Am Dyskinetic? A fMRI Case Report in Parkinson Disease

open access: yesFrontiers in Psychology, 2020
BackgroundThe identical sets of neurons – the mirror neuron system (MNS) – can be activated by simply observing specific, specific movements, decoded behaviors and even facial expressions performed by other people.
Sara Palermo   +10 more
doaj   +1 more source

Bidirectional Control of Absence Seizures by the Basal Ganglia: A Computational Evidence [PDF]

open access: yes, 2014
Absence epilepsy is believed to be associated with the abnormal interactions between the cerebral cortex and thalamus. Besides the direct coupling, anatomical evidence indicates that the cerebral cortex and thalamus also communicate indirectly through an important intermediate bridge--basal ganglia.
arxiv   +1 more source

Confluent Thalamic Hyperintensities in CADASIL [PDF]

open access: yes, 2010
Background: CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions.
Chabriat, Hugues   +6 more
core   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

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