Results 141 to 150 of about 140,652 (287)
Evaluating Reproductive Health Recommendations in CPGs for Sickle Cell Disease: An Umbrella Review
Clinical and Public Health Guidelines, Volume 3, Issue 4, October 2026.ABSTRACT Background Individuals with sickle cell disease or trait (SCD/T) face significant reproductive health risks, highlighting the need to assess the best available evidence on their reproductive health needs. Objectives To assess the quality of SCD/T clinical practice guidelines and evaluate the key characteristics and quality of their ...
Lisa R. Roberts +4 more
wiley +1 more source
Research in Molecular Medicine, 2017 Alpha Thalassemia is one of the most prevalent disorders worldwide with a [T1] high carrier rate in Mazandaran province (north of Iran). Carriers of --MED double gene deletion are at risk of having a child with hemoglobin haemoglobin[T2]
Hossein Jalali +3 more
doaj
Probing Red Blood Cell Deformability in Sickle Cell Disease, Sickle Cell Trait, and Healthy Controls by Ektacytometry [PDF]
EJHaemABSTRACT Introduction Red blood cell (RBC) deformability is a key determinant of sickle cell disease (SCD) pathophysiology. We evaluated RBC deformability across HbSS, HbAS, and HbAA genotypes and investigated its associations with hemolysis, fetal hemoglobin (HbF), coinherited α‐thalassemia, hydroxyurea treatment, and the PIEZO1 E756del variant ...
Wang X +4 more
europepmc +2 more sources
Mutation analysis of β-thalassemia in East-Western Indian population: a recent molecular approach
, 2017 Parth S Shah,1 Nidhi D Shah,2 Hari Shankar P Ray,3 Nikunj B Khatri,3 Ketan K Vaghasia,3 Rutvik J Raval,4 Sandip C Shah,3 Mandava V Rao5 1Department of Medicine, Lahey Hospital and Medical Center, Boston, MA, 2Department of Pediatrics, Nassau University ...
Khatri NB +7 more
core
Peripheral Blood Lymphocytosis Reflecting an Underlying Thymoma
American Journal of Hematology, Volume 101, Issue 10, Page 2652-2653, October 2026.
Léa Ousset +2 more
wiley +1 more source
Human erythroid models of sickle cell disease
HemaSphere, Volume 10, Issue 10, October 2026.Abstract Sickle cell disease (SCD) is a group of severe inherited red blood cell disorders causing a major global healthcare burden. Despite recent advances in gene therapy and stem cell transplantation, treatment options remain very limited, highlighting the urgent need for the development of new therapeutic approaches.
Deborah E. Daniels +5 more
wiley +1 more source
Deletional a-thalassemia 1 gene detection and hematological analysis in carrier with β-thalassemia
Journal of Associated Medical Sciences, 2012 There are high prevalence of β-thalassemia and α-thalassemia in the upper Northern Thailand. Thus, the interaction between β-thalassemia and α-thalassemia can be occurred.
Sitthichai Panyasai
doaj
American Journal of Hematology, Volume 101, Issue 10, Page 2666-2671, October 2026.
Kenneth I. Ataga +8 more
wiley +1 more source
EHA Guidelines on the management of children and adults with hemoglobin SC disease
HemaSphere, Volume 10, Issue 10, October 2026.Abstract HbSC disease is the second most common type of sickle cell disease (SCD) in populations of African origin. Although it is often grouped together with other types of SCD, particularly sickle cell anemia (HbSS), it has unique pathophysiology and a different spectrum of laboratory and clinical features.
David C. Rees +15 more
wiley +1 more source
The Need to Establish a G6PD Deficiency Patient Registry in Mazandaran Province: A Policy Brief [PDF]
Journal of Mazandaran University of Medical SciencesG6PD deficiency is an X-linked recessive disorder affecting more than 500 million people worldwide. The enzyme plays a critical role in generating NADPH, thereby protecting red blood cells against oxidative stress; exposure to fava beans, certain drugs ...
Hossein Karami +3 more
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