Results 131 to 140 of about 140,652 (287)

Causes of Death and Mortality Trends in Individuals with Thalassemia in the United States, 1999-2020 [PDF]

Jia Yi Tan,1 Yong Hao Yeo,2 Kok Hoe Chan,3 Hamid S Shaaban,4 Gunwant Guron4 1Department of Internal Medicine, New York Medical College at Saint Michael’s Medical Center, Newark, NJ, USA; 2Department of Internal Medicine/Pediatrics, Corewell Health, Royal
Guron G, Chan KH, Yeo YH, Tan JY, Shaaban HS   +4 more
core  

Thalassemia intermedia: An overview [PDF]

, 2012
β-Thalassemia is considered the most common chronic hemolytic anemia in Egypt. Patients with β-thalassemia whose anemia is not so severe as to necessitate regular transfusions are said to have thalassemia intermedia.
Shawky, RM, Kamal, TM
core  

Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.

, 2013
Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.
Chun-Ping Lin (285488), Fen-Ting Huang (285491), Ri-Xin Zeng (285499), Di-Hong Wu (285495), Hui Yang (91136), Yuan Wang (14955), Li-Ye Yang (285504), Qiu-Qing Weng (285490), Min Lu (238723), Hua Yang (120668), Hui-Zhou Chen (285493), Long-Xu Xie (285502), Yue Huang (285485), Jun-Li Wang (285503), Fen Lin (285486), Juan-Juan Zhu (285501), Gui-Cai Li (285500), Min Lin (17652), Xiao-Fen Zhan (285487), Jing-Bo Zeng (285498), Ying-Fang Wen (285483), Jiao-Ren Wu (285484), Gui-Rong Liu (80139), Mei-Qiong Yao (285492), Qian Wang (32718), Hui-Tian Yang (285489), Lei Zheng (106363)   +26 more
core   +1 more source

The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit, Kornkamon Lertsuwan, Natnicha Tannop, Ploypapus Lapatkeattisukul, Thanayuth Jenpichitkulchai, Nittiyaporn Sotapong, Jarinthorn Teerapornpuntakit, Tueanjai Khunluck, Siriwan Punvilai, Narattaphol Charoenphandhu   +9 more
wiley   +1 more source

GENETIC DISORDERS OF RED CELL GLYCOLYSIS : A REVIEW FROM THE MOLECULAR TO CLINICAL AND THERAPEUTIC APROACHES

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The erythrocyte, devoid of nucleus, mitochondria,ribosomes and other organelles, has no capacity for cell replication, protein synthesis, or oxidative phosphorylation.
SOPHIA DELICOU, THEONI KANELLOPOULOU, CHRYSSANTHI KONTAXI, ARGIRI VLACHOPOULOU, ZOI PALANTZA, KONSTANTINOS MARAGKOS   +5 more
doaj  

Osteoporosis in Thalassemia Major

, 2012
Talasemi Major inefektif eritropoez, kemik iliği ekspansiyonu ve iskelet deformitelerine neden olan kalıtsal bir kan hastalığıdır. Son yirmi yılda hastaların sağ kalımının belirgin şekilde uzamasıyla, osteoporoz ciddi bir sorun haline gelmiştir.
Rengin Güzel, Pembe Hare Yiğitoğlu
core   +1 more source

Psychometric properties of the Specific Thalassemia Quality of Life Instrument for adults

, 2012
Georgios N Lyrakos,1,2 Demetra Vini,2 Helen Aslani,2 Marouso Drosou-Servou212nd Department of Anesthesiology, School of Medicine, University of Athens, Pain Clinic, Attikon University Hospital, 2Thalassemia Unit, General Hospital of Nikaia Ag ...
Drosou-Servou M, Aslani H, Vini D, Lyrakos GN   +3 more
core  

A Novel Homozygous Frameshift Variant in ZNF699 Associated With DEGCAGS Syndrome With Severe Transfusion‐Dependent Anemia in an Indian Child: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In children with unexplained multisystem involvement—global developmental delay, dysmorphism, skeletal anomalies, and severe transfusion‐dependent anemia—especially from consanguineous families, whole‐exome sequencing should be pursued early to enable timely diagnosis, proactive iron chelation, and genetic counseling.
Arimanda Chaitanya Laasya Reddy, A. Vamshee Priya, Aditya Pachwa, Boilla Abhignya Reddy, Lakshya Nehal Samineni, Lanka Gourav Reddy   +5 more
wiley   +1 more source

Successful Management of Severe Hepatic Acute Graft‐Versus‐Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in a Child With β‐Thalassemia Major: Clinical Lessons From Early Therapeutic Escalation

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Severe hepatic acute graft‐versus‐host disease can occur early after allogeneic hematopoietic stem cell transplantation without skin involvement, presenting with rapidly progressive cholestatic liver dysfunction. Early recognition and prompt escalation to multimodal immunosuppressive therapy achieve complete biochemical remission and durable ...
Hind Alhiraki, Amal Ali Fares, Maged Kheder   +2 more
wiley   +1 more source

Cracking the cytokine code in sickle cell disease: Immune‐informatics for precision inflammation mapping, risk prediction and therapeutic discovery

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu, Chukwuma J. Okafor   +1 more
wiley   +1 more source