Results 191 to 200 of about 219,391 (317)

Evaluation of cardiac and hepatic iron overload in thalassemia major patients with T2* magnetic resonance imaging [PDF]

, 2017
Pustika Amalia Wahidiyat, Felix Liauw, Damayanti Sekarsari, Siti Ayu Putriasih, Vasili Berdoukas, Dudley J. Pennell   +5 more
openalex   +1 more source

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

Identification of a Neonate with Thalassemia Intermedia Despite Premarital Screening Program in Mazandaran Province (Co-inheritance of Hb Knossos and IVS II-1 G> A Mutations)

Research in Molecular Medicine, 2017
Background: Beta thalassemia is a common health problem in Iran especially in Northern provinces. Premarital screening for thalassemia is compulsory in Iran and identification of the carriers is based on primary CBC (Cell Blood Count) and hemoglobin ...
Hossein Karami, Hossein Jalali, Mehrad Mahdavi, Mohammad Reza Mahdavi   +3 more
doaj  

Matrix‐assisted Laser Desorption Ionization Mass Spectrometry for Detection of α/β‐Chain Changes From Human Hemoglobin: An Exploratory Study

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT In this work, we developed a matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry (MALDI‐TOF‐MS) method to directly analyze human whole blood samples. 1.0 µL of whole blood samples and 1.0 µL of optimized organic matrix were directly loaded onto the sample plates for MALDI‐TOF‐MS detection.
Dan‐ping Liu, Bi‐cheng Yang, Qiao‐yun Huang, Ping Liu, Hai‐yan Luo, Mao‐lin Yu, Jian‐qiong Yang, An Jia, Yan‐qiu Liu, Lin Xu, Bin Hu, Ting Huang   +11 more
wiley   +1 more source

Pediatric Cervicofacial Necrotizing Fasciitis: A Case Report Highlighting the Diagnostic Challenges and Management in a Child Without Preceding Trauma or Infection

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Necrotizing fasciitis (NF) is a rare but serious life‐threatening condition in children that can be easily overlooked due to its atypical presentation and absence of common risk factors. This case involves a 10‐year‐old girl with a history of non‐transfusion‐dependent thalassemia and epilepsy who developed cervicofacial NF without any prior ...
Anza Muhammad Mohsin, Zahra Anas, Zarlish Khan, Muhammad Abdullah Bin Fahad   +3 more
wiley   +1 more source

ATRX: From Chromatin Remodeling to Disease

genesis, Volume 63, Issue 6, December 2025.
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta, Viviana Valadez‐Graham   +1 more
wiley   +1 more source

Lack of awareness about thalassemia; a social factor in the propagation of beta thalassemia gene in Pakistan: A population study

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Background: Beta thalassemia is the most common genetic disorder in Pakistan. Thalassemia is a preventive disease a fact well demonstrated by countries such as Italy, Greece and Cyprus.
Muhammad Usman
doaj  

Interscanner reproducibility of cardiovascular magnetic resonance T2* measurements of tissue iron in thalassemia [PDF]

, 2003
Mark A. Westwood, Lisa Anderson, David Firmin, Peter Gatehouse, Christine H. Lorenz, B. Wonke, Dudley J. Pennell   +6 more
openalex   +1 more source

Antenatal dexamethasone for late preterm delivery: Rate of complete course and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 1180-1188, December 2025.
Abstract Objective This retrospective cohort study aimed to assess the rate of complete dexamethasone administration among late preterm deliveries and its impact on neonatal outcomes. Methods We reviewed medical records of 1500 late preterm deliveries (gestational age 34–36 + 6 weeks) between January 2018 and December 2020, analyzing baseline ...
Piyamon Srisakulpanich, Pattarawalai Talungchit, Tachjaree Panchalee, Chutima Yaiyiam   +3 more
wiley   +1 more source

Identification of maternal ^Gγ(^Aγδβ)⁰ thalassemia through retrospective reanalysis of prenatal cfDNA sequencing data. [PDF]

Ann Med
Zhu X, Hu L, Pei Y, Ran J, Wen L, Zhong J, Zhu Y, Zeng K, Wei F, Liu W.   +9 more
europepmc   +1 more source