Results 221 to 230 of about 181,456 (327)

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Jose L. Domingo
wiley   +1 more source

Efficacy and safety of deferiprone for thalassemia: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Syst Rev
Wilar G, Suhandi C, Kawahata I.
europepmc   +1 more source

Treatment with bosentan in a patient with thalassemia intermedia and pulmonary arterial hypertension [PDF]

, 2012
Anastasia Anthi, Iraklis Tsangaris, E. Hamodraka, John Lekakis, Apostolos Armaganidis, Stylianos E. Orfanos   +5 more
openalex   +1 more source

Cerebral blood flow trajectories in paediatric sickle cell anaemia by age, region, and treatment associations

British Journal of Haematology, Volume 208, Issue 1, Page 367-372, January 2026.
Opposite to the age trend in healthy children, cerebral blood flow increases with age in children with sickle cell anaemia. Early treatment with hydroxyurea (hydroxycarbamide) may help slow this abnormal trend and protect brain functions.
Ping Zou Stinnett, Robert J. Ogg, Kathleen Helton, Winfred Wang, Andrew M. Heitzer, Zachary Abramson, Yimei Li, Tushar Patni, Paul VanGilder, Akshay Sharma, Ranganatha Sitaram   +10 more
wiley   +1 more source

HbE/β-thalassemia presenting with Moyamoya angiopathy-associated ischemic stroke and noncompressive intrathoracic extramedullary hematopoiesis. [PDF]

Neurol Perspect
Ghosh R, León-Ruiz M, Das S, Dubey S, Benito-León J.   +4 more
europepmc   +1 more source

Achieving clinically meaningful changes in haemoglobin levels in patients with non‐transfusion‐dependent β‐thalassaemia treated with luspatercept: A post hoc analysis of the phase 2 BEYOND trial

British Journal of Haematology, Volume 208, Issue 1, Page 348-352, January 2026.
In this post hoc analysis of the phase 2 BEYOND trial, the majority of patients with non‐transfusion‐dependent β‐thalassaemia achieved clinically meaningful haemoglobin levels ≥10.0 g/dL and increases from baseline ≥1.0 g/dL, thresholds associated with reduced risk of morbidity and mortality and recommended as an indication and target for treatment by ...
Khaled M. Musallam, Ali T. Taher, John B. Porter, Antonis Kattamis, Mrudula B. Glassberg, Luciana Moro Bueno, Patricia Martin‐Regueira, Marta Reverte, Loyse Felber Medlin, Matthew Dyer, Kefeng Wang, Maria Domenica Cappellini   +11 more
wiley   +1 more source

Beyond anemia: unraveling neutrophil defects and infection susceptibility in β-Thalassemia. [PDF]

Blood Res
Asadov C, Aliyeva G.
europepmc   +1 more source

Screening extended families for genetic hemoglobin disorders in Pakistan [PDF]

, 2002
Ahmed, S, Modell, B, Petrou, M, Saleem, M   +3 more
core   +1 more source

Iron‐related intercellular communication in the liver: Main players and mechanisms

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Iron exchange between liver cell types is vital for organism health, yet its mechanisms remain poorly understood. In this review, we address intercellular communication governing hepatic iron regulation across different liver diseases. We summarize recent insights into how hepatocytes, macrophages, endothelial and stellate cells coordinate iron storage,
Óscar Fonseca, Paulo J. Oliveira, Martina U. Muckenthaler, Ana C. Moreira, M. Salomé Gomes   +4 more
wiley   +1 more source

Importance of the 3'UTR region in globin synthesis: identification of two novel HBA1 mutations causing α-Thalassemia. [PDF]

Ann Hematol
Benito SF, Abío M, Bardón-Cancho EJ, Nieto JM, Ortega B, González FA, Villegas A, Benavente C, Ropero P.   +8 more
europepmc   +1 more source