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Pediatric Clinics of North America, 2013
The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation.
Alissa, Martin, Alexis A, Thompson
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The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation.
Alissa, Martin, Alexis A, Thompson
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Human Fertility, 2016
Beta-thalassemia (BTM) major is the most common haemoglobin disorder in the world, with high prevalence in people of Mediterranean, Arab or Asian origin. It has been estimated that about 1.5% of the global population (80-90 million people) are carriers of BTM.
Castaldi, Maria Antonietta +1 more
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Beta-thalassemia (BTM) major is the most common haemoglobin disorder in the world, with high prevalence in people of Mediterranean, Arab or Asian origin. It has been estimated that about 1.5% of the global population (80-90 million people) are carriers of BTM.
Castaldi, Maria Antonietta +1 more
openaire +5 more sources
Management of age-associated medical complications in patients with β-thalassemia
Expert Review of Hematology, 2020Introduction: β-Thalassemia syndromes are among the most common monogenic disorders worldwide. Clinically, on the basis of the severity of the phenotype, β-thalassemias are classified into two groups: transfusion-dependent thalassemia (TDT) and non ...
I. Motta +4 more
semanticscholar +1 more source
Thalassemia and hypercoagulability
Blood Reviews, 2008Thalassemia is a congenital hemolytic disease caused by defective globin synthesis resulting in decreased quantity of globin chains. Although the life expectancy of beta-thalassemia patients has markedly improved over the last few years, patients still suffer from many complications of this congenital disease.
A. T. Taher +3 more
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Minerva Ginecologica, 2018
Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman.
S. J. Matthews +3 more
semanticscholar +1 more source
Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman.
S. J. Matthews +3 more
semanticscholar +1 more source
Hematology/Oncology Clinics of North America, 2023
Edward J, Benz, Vijay G, Sankaran
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Edward J, Benz, Vijay G, Sankaran
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Clinical Obstetrics and Gynecology, 1995
The responsibility of the obstetrician is to identify during the first trimester women who are carriers for thalassemia. When she has been identified, the father of the baby should be screened and if he is also a carrier, the couple should be offered prenatal diagnosis.
Russell K. Laros, Sarah J. Kilpatrick
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The responsibility of the obstetrician is to identify during the first trimester women who are carriers for thalassemia. When she has been identified, the father of the baby should be screened and if he is also a carrier, the couple should be offered prenatal diagnosis.
Russell K. Laros, Sarah J. Kilpatrick
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Pathophysiology of thalassemia
Current Opinion in Hematology, 2002Despite discoveries concerning the molecular abnormalities that led to the thalassemic syndromes, it still is not known how accumulation of excess unmatched alpha-globin in beta thalassemia and beta-globin in alpha thalassemia leads to red blood cell hemolysis in the peripheral blood, and in the beta thalassemias particularly, premature destruction of ...
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The Journal of Perinatal & Neonatal Nursing, 2003
Thalassemia syndromes, hemoglobinopathies characterized by anemia secondary to genetic defects of hemoglobin, are the most common of the genetic blood disorders. The prevalence and severity of the thalassemia syndromes are population dependent, with the type of thalassemia seen dependent on racial background. The health care provider must recognize the
openaire +3 more sources
Thalassemia syndromes, hemoglobinopathies characterized by anemia secondary to genetic defects of hemoglobin, are the most common of the genetic blood disorders. The prevalence and severity of the thalassemia syndromes are population dependent, with the type of thalassemia seen dependent on racial background. The health care provider must recognize the
openaire +3 more sources