Results 21 to 30 of about 158,916 (259)

TyG index and insulin resistance in beta-thalassemia [PDF]

open access: yes, 2015
Insulin resistance (IR) underlies some glucose metabolism abnormalities in thalassemia major. Recently, triglyceride glucose index (TyG) has been proposed for evaluating insulin resistance as a simple, low cost, and accessible tool.
Fayaz, M.   +3 more
core   +1 more source

Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]

open access: yes, 2014
Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas   +5 more
core   +1 more source

Thalassemia [PDF]

open access: yesCanadian Medical Association Journal, 2020
Hayley, Merkeley, Lauren, Bolster
  +5 more sources

Heterozygous β-thalassemia with thalassemia intermedia phenotype [PDF]

open access: yesAmerican Journal of Hematology, 1998
In this study we investigated the molecular bases of the beta-thalassemia intermedia phenotype in six patients belonging to two unrelated families of Sardinian descent. Sequence analysis of the beta globin gene from these patients detected, as the sole abnormality, the heterozygosity for the codon 39 nonsense mutation.
D, Gasperini   +7 more
openaire   +2 more sources

Effect of a+ -thalassaemia on episodes of fever due to malaria and other causes: a communitybased cohort study in Tanzania [PDF]

open access: yes, 2011
Background It is controversial to what degree a+-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium. Methods In Tanzania, in children aged 6-60 months and height-for-age z-score
Baidjoe, A.Y.   +7 more
core   +5 more sources

Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

open access: yesScientific Reports, 2022
Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri   +7 more
doaj   +1 more source

Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials

open access: yesВопросы вирусологии, 2022
COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram   +6 more
doaj   +1 more source

Methods to assess iron and iodine status [PDF]

open access: yes, 2008
Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin.
Zimmermann, M.B.
core   +2 more sources

Let’s talk about thal: How communication can improve quality of life

open access: yesThalassemia Reports, 2018
In many parts of the world, research, improved technology, and better medicine have enabled people with thalassemia to live longer. It is tragic that due to global disparity in healthcare, in areas of the world where thalassemia is most prevalent, the ...
Laurice M. Levine
doaj   +1 more source

Thalassemia

open access: yesTrends in Pediatrics, 2021
Defects in protein structure or synthesis of hemoglobin are called hemoglobinopathies. Thalassemia is the most common hemoglobinopathy, and it is estimated that 5% of the world population carries at least one variant allele of thalassemia. The thalassemias can be classified as alpha or beta thalassemias.
Tekin Aksu, Sule Unal
openaire   +3 more sources

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