Results 21 to 30 of about 140,103 (295)

Fertility in Patients with Thalassemia and Outcome of Pregnancies: A Turkish Experience

open access: yesTurkish Journal of Hematology, 2019
Objective: In recent years, the rates of marriage and pregnancy are increasing in patients with thalassemia major. The aim of the present study was to investigate the fertility rate of thalassemic patients and the course of pregnancies in terms of mother
Burcu Akıncı   +8 more
doaj   +1 more source

Potential Effects of Silymarin and Its Flavonolignan Components in Patients with β-Thalassemia Major: A Comprehensive Review in 2015

open access: yesAdvances in Pharmacological Sciences, 2016
Major β-thalassemia (β-TM) is one of the most common inherited hemolytic types of anemia which is caused as a result of absent or reduced synthesis of β-globin chains of hemoglobin. This defect results in red blood cells lysis and chronic anemia that can
Hadi Darvishi Khezri   +5 more
doaj   +1 more source

Phosphaturia in Thalassemia

open access: yesPediatrics, 1976
Thirteen phosphorus balances were performed in four thalassemic children aged 6 to 10 years. No correlation was found between phosphorus intake and serum level or between phosphorus intake and net absorption. There was a positive correlation among daily phosphorus intake, net absorption, and 24-hour urinary excretion.
Lapatsanis, P.   +4 more
openaire   +3 more sources

PREGNANCY IN THALASSEMIA

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2019
Therapeutic advances, including the availability of oral iron chelators and new non-invasive methods for early detection and treatment of iron overload, have significantly improved the life expectancy and quality of life of patients with thalassemia, with a consequent increase in their reproductive potential and desire to have children.
Raffaella Origa, Federica Comitini
openaire   +4 more sources

Let’s talk about thal: How communication can improve quality of life

open access: yesThalassemia Reports, 2018
In many parts of the world, research, improved technology, and better medicine have enabled people with thalassemia to live longer. It is tragic that due to global disparity in healthcare, in areas of the world where thalassemia is most prevalent, the ...
Laurice M. Levine
doaj   +1 more source

Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

open access: yesScientific Reports, 2022
Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri   +7 more
doaj   +1 more source

Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials

open access: yesВопросы вирусологии, 2022
COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The shortcut strategy for beta thalassemia prevention

open access: yesHematology Reports, 2018
We propose antenatal blood tests using high-resolution DNA melting (HRM) analysis for beta thalassemia mutation detection after hemoglobin A2 estimation as a modified strategy for the identification of beta thalassemia at-risk couples.
Narutchala Suwannakhon   +6 more
doaj   +1 more source

Management of the Thalassemias [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2013
During the last 30 years, in addition to the considerable progress made in control and prevention of thalassemias(3), there have also been major advances in their symptomatic management, at least in wealthier countries where appropriate facilities are available.
Nancy F, Olivieri, Gary M, Brittenham
openaire   +2 more sources

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