Results 41 to 50 of about 140,652 (287)

The Presence and Percentage of Circulating Nucleated Red Blood Cells Reveal Distinct Characteristics in Adults With Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco   +7 more
wiley   +1 more source

Components of an effective large scale program for the prevention of inherited hemoglobin disorders; the paradigm of Greece

open access: yesThalassemia Reports, 2012
Large scale prevention programs for Thalassemia major or Sickle cell disease have already been set up in several places with high frequency of the deleterious genes.
D. Loukopoulos   +2 more
doaj   +1 more source

Thalassemia and the Heartquake

open access: yesThalassemia Reports, 2014
On May 2012 the city of Ferrara and the surrounding region were hit by several earthquakes. We had the chance to observe the behavior of one thalassemic heart during the shocks, because of a 24-h electrocardiogram recording had been put in place a few hours before the shocks.
Caterina Borgna-Pignatti   +3 more
openaire   +4 more sources

Demographic characteristics of children with thalassemia versus without thalassemia.

open access: yes, 2021
Demographic characteristics of children with thalassemia versus without thalassemia.
Chuan-Pin Lee (3716623)   +9 more
core   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

open access: yesBiotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga   +2 more
wiley   +1 more source

Unravelling the Complexity of the +33 C>G [HBB:c.-18C>G] Variant in Beta Thalassemia

open access: yesBiomedicines
The +33 C>G variant [NM_000518.5(HBB):c.-18C>G] in the 5′ untranslated region (UTR) of the β-globin gene is described in the literature as both mild and silent, while it causes a phenotype of thalassemia intermedia in the presence of a severe β ...
Coralea Stephanou   +7 more
doaj   +1 more source

INHERITED BONE MARROW FAILURE SYNDROMES WITH PANCYTOPAENIA [PDF]

open access: yesEuropean Medical Journal Hematology, 2014
Bone marrow failure (BMF) is characterised by a reduction in the effective production of mature erythrocytes, granulocytes, and platelets by the bone marrow that leads to peripheral blood pancytopaenia.
Sophia Delicou   +5 more
doaj  

Identification of optimal thalassemia screening strategies for migrant populations in Thailand using a qualitative approach

open access: yesBMC Public Health, 2021
Background Thalassemia is a common inherited hemoglobin disorder in Southeast Asia. Severe thalassemia can lead to significant morbidity for patients and economic strain for under-resourced health systems.
Julia Z. Xu   +8 more
doaj   +1 more source

Hazard ratio of thalassemia to non-thalassemia children had asthma.

open access: yes, 2021
Hazard ratio of thalassemia to non-thalassemia children had asthma.
Chuan-Pin Lee (3716623)   +9 more
core   +1 more source

The Vanishing Myocardium in Severe Myocardial Iron Overload

open access: yesiRADIOLOGY, EarlyView.
Heart failure due to severe myocardial iron overload is the leading cause of death in transfusion‐dependent thalassemia. Cardiovascular magnetic resonance is essential for detecting myocardial iron overload and grading its severity.
Firas Khana, Alae Kayyali
wiley   +1 more source

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