Results 81 to 90 of about 107,712 (298)

Potential Therapeutic Actions of Flavonoids Present in Propolis That Modulate Vascular Endothelial Growth Factor Signaling to Regulate Angiogenesis

Phytotherapy Research, EarlyView.
ABSTRACT Propolis is a plant‐derived substance collected by honeybees that has a range of potential therapeutic applications. Propolis consists of resins, waxes, and fatty acids, as well as essential oils and other organic compounds. The pharmacologically active components of propolis include phenols and flavonoids, among others.
Yipeng Lin, Janney Z. Wang, Yihe Niu, Ling Zhu, Rujee K. Duke, Colin C. Duke, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

PAIN MANAGEMENT IN PATIENTS WITH SICKLE CELL DISEASE – A REVIEW [PDF]

European Medical Journal Hematology, 2013
Pain is defined, by the International Association for the Study of Pain (IASP), as an ‘unpleasant sensitive and emotional experience, associated with or described in terms of tissue lesion’.
Sophia Delicou, Konstantinos Maragkos
doaj  

A Case of Severe Anemia in Pregnancy Treated With Traditional Chinese Medicine. [PDF]

Clin Case Rep
ABSTRACT This case report describes the treatment of a 29‐year‐old pregnant woman with severe anemia using traditional Chinese medicine (TCM). The patient, at 5 weeks of gestation, presented with a hemoglobin level of 75 g/L and had a history of autoimmune hemolytic anemia and alpha‐thalassemia, which had previously led to pregnancy termination at 17 ...
Zhong S, Xie T.
europepmc   +2 more sources

Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia.

Blood, 2019
The thalassemias are compelling targets for therapeutic genome editing in part because monoallelic correction of a subset of hematopoietic stem cells (HSCs) would be sufficient for enduring disease amelioration.
Shuqian Xu, Kevin Luk, Qiuming Yao, Anne H. Shen, Jing Zeng, Yuxuan Wu, Hong‐yuan Luo, C. Brendel, Luca Pinello, D. Chui, S. Wolfe, D. E. Bauer   +11 more
semanticscholar   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

PB2240: SILENT GLOBIN MUTATIONS. 10 YEARS REFERRALS FOR GENETIC COUNSELING.

HemaSphere, 2022
S. Theodoridou, A. Teli, E. Boutou, E.-E. Delaki, E. Yfanti, V. Efthimia, E. Zarkada, A. Balassopoulou   +7 more
doaj   +1 more source

Elevated Prevalence of Abnormal Glucose Metabolism and Other Endocrine Disorders in Patients with β-Thalassemia Major: A Meta-Analysis

BioMed Research International, 2019
Background Endocrinopathies are common in patients with β-thalassemia major despite parenteral iron chelation therapy with deferoxamine. Prevalence of abnormal glucose metabolism in previous studies was controversial. The aim of this study was to discuss
Li-Na He, Wei Chen, Yi Yang, Ying-jun Xie, Zeyu Xiong, Diyu Chen, Dian Lu, Nengqing Liu, Yinghong Yang, Xiao-Fang Sun   +9 more
semanticscholar   +1 more source

Risk of priapism after dynamic penile Doppler ultrasound: Single‐centre experience on a large cohort of patients

Andrology, EarlyView.
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande, Andrea Graziani, Raffaele Scafa, Andrea Delbarba, Nicola Caretta, Pierfrancesco Palego, Alberto Ferlin   +6 more
wiley   +1 more source

PB2541: RARE CAP +41 TO +44 [HBB:C.11_-8DELAAAC]/NI MUTATION IN THE 5;UTR OF THE Β GLOBIN GENE IN A GREEK MALE AND GENETIC COUNSELING.

HemaSphere, 2023
Stamatia Theodoridou, Evaggelia-Eleni Delaki, Eleni Yfanti, Aikaterini Teli, Genovefa Mantzou, Christina Karipidou, Maria Dimopoulou   +6 more
doaj   +1 more source

How I manage medical complications of β-thalassemia in adults.

Blood, 2018
The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis ...
A. Taher, M. Cappellini
semanticscholar   +1 more source