Results 91 to 100 of about 140,103 (295)

Epidemiological and comorbidity burden in transfusion-dependent patients with thalassemia and sickle cell disease in Greece

Annals of Hematology
TDT and SCD are hereditary hemoglobinopathies that require lifelong red blood cell transfusions. Modern treatment has increased survival, exposing patients to transfusion-related problems such iron excess.
Sophia Delicou, Aikaterini Xydaki, Vassiliki Kamposou, Sabrina Goga, Anthimos Papadopoulos, Christina Rina, Maria Moraki   +6 more
doaj   +1 more source

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

European Journal of Haematology, EarlyView.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni, Sara Vinagre Enríquez, Marta Villalon Herrera, Mercedes Plaza Fornieles, Iván López Torija, Andrea Urtasun Erburu, Laura Alonso García, Alexandra Regueiro García, Maria Trabazo del Castillo, Eduardo J. Bardón‐Cancho, Odelaisy León‐Triana, Carla Miñarro Chacón, José Luís Fuster Soler, Antonio Pérez‐Martínez, Pascual Balsalobre López, Marta Gonzalez‐Vicent, Cristina Díaz de Heredia, on behalf of the GETH‐TC Pediatric Working Group   +17 more
wiley   +1 more source

Thailand's Emerging Role in the Cell and Gene Therapy Revolution: A Review of Progress and Potential

Clinical and Translational Science
This Perspective examines Thailand's role in cell and gene therapy, focusing on regulatory development and early clinical experience. These therapies are used in Thailand for β‐thalassemia, or blood cancer, together with the evolving ATMP regulatory ...
Vip Viprakasit, Warut Tulalamba, Thidarat Suksangpleng, Supachai Ekwattanakit   +3 more
doaj   +1 more source

A beta-thalassemia carrier with normal sequence within the beta-globin gene [letter] [PDF]

, 1990
S Murru, Georgios Loudianos, Aili Cao, Simona Vaccargiu, Mario Pirastu, GV Sciarratta, Steven J. Agosti, MI Parodi   +7 more
openalex   +1 more source

Free Fetal DNA Testing to Guide Early Intervention in the Management of the Kell Alloimmunized Pregnancy

Prenatal Diagnosis, EarlyView.
Kenneth J. Moise Jr, Thomas Trevett, Stephanie Moench, Erin Moise   +3 more
wiley   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

The emerging role of non-coding RNAs in the pathogenesis of infantile hemangioma

Cancer Cell International
Infantile hemangioma (IH) is a common benign tumor that occurs in children, affecting both blood vessels and soft tissues. Its pathological features include abnormal proliferation of endothelial cells and an irregular vascular structure.
Najmaldin Saki, Narjes Sadat Sadati, Zeinab Deris Zayeri, Masoud Kargar   +3 more
doaj   +1 more source

Thalassemia and Hemoglobin E in Southern Thai Blood Donors

Advances in Hematology, 2014
Thalassemia and hemoglobin E (Hb E) are common in Thailand. Individuals with thalassemia trait usually have a normal hemoglobin concentration or mild anemia. Therefore, thalassemic individuals who have minimum acceptable Hb level may be accepted as blood
Manit Nuinoon, Kwanta Kruachan, Warachaya Sengking, Dararat Horpet, Ubol Sungyuan   +4 more
doaj   +1 more source

Osteoporosis and Associated Factors among Thalassemia Patients Referred to Bone Mineral Density Screening -Dubai Hospital, 2014-2017 [PDF]

, 2017
M. Mohseni Zadeh, Hamid Yahya Hussain, Waleed Al Faisal, Muhammed Muhasin   +3 more
openalex   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source