Results 61 to 70 of about 5,420,950 (275)

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Seroprevalence of HCV Antibody among Patients with β-Thalassemia Major in Amirkola Thalassemia Center, Iran

Iranian Journal of Allergy, Asthma and Immunology, 2007
β- thalassemia major is a common hemoglobinopathy in humans. In some journals, numerous studies have reported different prevalence of hepatitis C among β- thalassemia major because thalassemic patients need multiple blood transfusions and blood ...
Ahmad Tamaddoni, Iraj Mohammadzadeh, Omid Ziaei   +2 more
doaj  

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Copper Status in Major Thalassemia Patients in Zahedan South East of Iran

International Journal of Hematology-Oncology and Stem Cell Research, 2013
Introduction: There have been many reports and papers on deficient, normal and high levels of copper in patients with thalassemia major. The aim of this study is to evaluate copper status in a series of more than 300 patients with thalassemia major and ...
Mohamad Ali Mashhadi
doaj  

Risk of priapism after dynamic penile Doppler ultrasound: Single‐centre experience on a large cohort of patients

Andrology, EarlyView.
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande, Andrea Graziani, Raffaele Scafa, Andrea Delbarba, Nicola Caretta, Pierfrancesco Palego, Alberto Ferlin   +6 more
wiley   +1 more source

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major.

Blood, 2016
Cardiovascular disease resulting from iron accumulation is still a major cause of death in patients with thalassemia major (TM). Voltage-gated calcium-channel blockade prevents iron entry into cardiomyocytes and may provide an adjuvant treatment to ...
J. Fernandes, S. Loggetto, Mônica P A Veríssimo, K. Fertrin, G. Baldanzi, L. A. Fioravante, D. Tan, T. Higa, D. A. Mashima, A. Piga, O. Coelho, F. Costa, S. Saad   +12 more
semanticscholar   +1 more source

Epidemiological Characteristics and Family Relatives among Thalassemic Patients in Sulaimani City, Kurdistan Region, Iraq

Kurdistan Journal of Applied Research, 2018
Thalassemia is a well-known inherited hematologic disorder caused by a decrease or an absence of globin production. Patients with thalassemia suffer from chronic hemolytic anemia and its sequelae.
Kamal Jalal Rashid
doaj   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Copper Status in Patients with Thalassemia Major in Zahedan, Iran

International Journal of Hematology-Oncology and Stem Cell Research, 2013
Introduction: There have been many reports and papers on deficient, normal and high levels of copper in patients with thalassemia major. The aim of this study is to evaluate copper status in a series of more than 300 patients with thalassemia major and ...
Mohamad Ali Mashhadi
doaj  

Comparative efficacy of varicocelectomy and intrauterine insemination in varicocoele patients with mild semen abnormalities: An observational study

Andrology, EarlyView.
Abstract Background Varicocoele is a common cause of male infertility, affecting spermatogenesis through increased testicular temperature, venous stasis, and oxidative stress. Microsurgical subinguinal varicocelectomy improves semen quality, whereas intrauterine insemination is widely used for mild male factor infertility.
Yanlin Ma, Weiming Deng, Tingting Wu, Qi Li, Yuanjie Li, Wenjie Mai, Lizheng Yan, Changwei Liang, Lingxiao Zhang   +8 more
wiley   +1 more source