Results 91 to 100 of about 41,191 (306)

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Light‐Imprinted Chirality in Nanomaterials: From Principles to Applications

Advanced Science, EarlyView.
Light‐induced chirality represents a transformative paradigm for fabricating chiral nanostructures. This review provides a comprehensive framework encompassing light‐based strategies for imprinting and tuning chirality in nanomaterials, which guides researchers in harnessing light to create next‐generation functional materials.
Xinru Jin, Emiliano Cortés, Alexander O. Govorov, Tao Ding   +3 more
wiley   +1 more source

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

Advanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li, Hongtao Zhang, Zichao Peng, Yuheng Zhang, Qian Lv, Yihuan Cao, Xuqing Wang, Huadong Fu, Jianxin Xie   +8 more
wiley   +1 more source

Interlayer‐Sliding‐Enabled Multiferroicity and Giant Switchable Anomalous Hall Conductivity in RuO2Zn2F2 Bilayer

Advanced Science, EarlyView.
Interlayer sliding in the RuO2Zn2F2 bilayer induces ferroelectricity and enables reversible valley polarization switching. The electric dipole and valley‐resolved band edges are intimately coupled, revealing sliding ferroelectricity as a powerful mechanism for electrical control of valley degrees of freedom in 2D materials.
Djamel Bezzerga, Imran Khan, Ganie Suhail Ahmad, Jisang Hong   +3 more
wiley   +1 more source

Ultrafast Dynamics of Spin Current and Electron Temperature in Spintronic Terahertz Emitters

Advanced Science, EarlyView.
This work quantifies optical‐pump‐induced THz transmission variations to reveal electron and lattice temperature dynamics and presents time‐resolved THz spectral maps for sub‐picosecond analysis. A 63 ± 8 fs time lag between THz emission and laser excitation is identified, serving as an intrinsic parameter limiting the upper frequency of spintronic THz
Yifan Wang, Zuanming Jin, Miao Cai, Zhiqiang Lan, Zhenjie Ge, Zheng Feng, Wei Tan, Alexei V. Balakin, Alexander P. Shkurinov, Yan Peng, Yiming Zhu   +10 more
wiley   +1 more source

Kinetics of Decomposition in Alkaline Media NaOH and Ca(OH)₂ of Thallium Jarosite

ChemEngineering
Thallium is one of the most toxic elements on the planet, and one alternative method for its precipitation is through jarosite-type compounds. Therefore, in this work, the kinetics of thallium jarosite were evaluated in an alkaline medium (NaOH and Ca(OH)
Hernán Islas, J. Eliecer Méndez, Francisco Patiño, Sayra Ordoñez, Iván A. Reyes, Paola B. Bocardo, Martín Reyes, Miriam Estrada, Mizraim U. Flores   +8 more
doaj   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Interpretable Machine Learning Framework for Nb─Si Based Alloy Design with Enhanced Fracture Toughness

Advanced Science, EarlyView.
An interpretable machine learning framework integrating SHAP and PDP analysis identifies critical design descriptors from 139 physicochemical features for Nb─Si alloys. The framework achieves <7% prediction error and guides the discovery of Nb38.5Ti38.5Si3Zr18V2 alloy with 22.791 MPa·m1/2 fracture toughness, breaking the 20 MPa·m1/2 barrier.
Dezhi Chen, Chao Xu, Jingyue Yu, Qi Wang, Hongze Fang, Shuo Yin, Turab Lookman, Ruirun Chen   +7 more
wiley   +1 more source

Thallium Toxicity: Mechanisms of Action, Available Therapies, and Experimental Models

Future Pharmacology
Thallium (Tl) is a non-essential and highly toxic heavy metal capable of replacing potassium (K+) in biological systems, leading to mitochondrial dysfunction, oxidative stress, and inhibition of protein synthesis.
Karla Alejandra Avendaño-Briseño, Jorge Escutia-Martínez, José Pedraza-Chaverri, Estefani Yaquelin Hernández-Cruz   +3 more
doaj   +1 more source

Trap Depth Modulation and Antenna Effect of Organic Ligands for Enhancing Rare‐Earth Long Persistent Luminescence

Advanced Science, EarlyView.
Different from the current research trends that mainly focus on optimizing a single color system, a universal organic–inorganic hybrid strategy is proposed, aiming to synergistically enhance the luminescent properties of red, green, and blue multi‐color inorganic long‐persistent phosphorescent materials by trap depth modulation and antenna effect of ...
Ting Tan, Nian Li, Bangmin Liu, Hao Wang, Xia Huang, Yuanjin Chen, Zhonghao Wang, Chaolong Yang   +7 more
wiley   +1 more source