Results 61 to 70 of about 583,007 (361)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Cervid herpesvirus 2 and not Moraxella bovoculi caused keratoconjunctivitis in experimentally inoculated semi-domesticated Eurasian tundra reindeer

open access: yesActa Veterinaria Scandinavica, 2017
Background Infectious keratoconjunctivitis (IKC) is a transmissible disease in semi-domesticated Eurasian reindeer (Rangifer tarandus tarandus). It is regarded as multifactorial and a single causative pathogen has not yet been identified.
Morten Tryland   +6 more
doaj   +1 more source

Sedimentary deformation relating to episodic seepage in the last 1.2 million years: a multi-scale seismic study from the Vestnesa Ridge, eastern Fram Strait

open access: yesFrontiers in Earth Science, 2023
Seafloor hydrocarbon seepage is a natural fluid release process that occurs worldwide on continental shelves, slopes, and in deep oceanic basins. The Vestnesa sedimentary ridge in the eastern Fram Strait hosts a deep-water gas hydrate system that became ...
Frances Cooke   +8 more
doaj   +1 more source

The tipping times in an Arctic sea ice system under influence of extreme events

open access: yes, 2020
In light of the rapid recent retreat of Arctic sea ice, the extreme weather events triggering the variability in Arctic ice cover has drawn increasing attention.
Duan, Jinqiao   +4 more
core   +1 more source

Arctic and Sub-Arctic Bees

open access: yesNature, 1898
OF the wild bees of Alaska nothing is known, except that several species of humble-bees (Bombus) are common. Consequently, when Mr. Trevor Kincaid wrote me last year that he was going to Alaska, and would collect bees, I was expecting to see, on his return, quite a new bee-fauna.
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Enigma of Interspecific Plasmodesmata: Insight From Parasitic Plants

open access: yesFrontiers in Plant Science, 2021
Parasitic plants live in intimate physical connection with other plants serving as their hosts. These host plants provide the inorganic and organic compounds that the parasites need for their propagation.
Karsten Fischer   +4 more
doaj   +1 more source

Arctic in Rapid Transition (ART) : science plan [PDF]

open access: yes, 2010
The Arctic is undergoing rapid transformations that have brought the Arctic Ocean to the top of international political agendas. Predicting future conditions of the Arctic Ocean system requires scientific knowledge of its present status as well as a ...
Forest, Alexandre   +9 more
core  

Polychlorinated biphenyls in air and water of the North Atlantic and Arctic Ocean. [PDF]

open access: yes, 2008
Air and seawater samples were collected on board the R/V Polarstern during a scientific expedition from Germany to the Arctic Ocean during June–August 2004.
Dachs, Jordi   +7 more
core   +3 more sources

Cystic echinococcosis in the Arctic and Sub-Arctic

open access: yesParasitology, 2003
The northern biotype ofEchinococcus granulosusoccurs throughout the holarctic zones of tundra and taiga, from eastern Fennoscandia to the Bering Strait in Eurasia and in North America from arctic Alaska approximately to the northern border of the United States.
openaire   +4 more sources

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