Results 81 to 90 of about 132,115,309 (296)

How dis-services illuminate divergence between “nature’s contribution to people” and “ecosystem services” – an assessment of Empetrum nigrum [PDF]

open access: yesOne Ecosystem
Encroachment of a native invasive species – Empetrum nigrum (crowberry) – has impacted Arctic ecosystems and the indigenous Sámi people. To understand comprehensively the impacts of this native invader, we adopted three concepts, ecosystem services (ES),
Pham Nhat   +3 more
doaj   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

The Inuvik Declaration, 1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada. [PDF]

open access: yes, 1996
The Inuvik Declaration, March 21,1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada.
Arctic Council, -
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Senior Arctic Official (SAO) Report to Ministers, Tromsø Norway, 2009 [PDF]

open access: yes, 2009
Arctic Council Senior Arctic Officials' (SAO) Report to Ministers.
Arctic Council, -
core   +1 more source

“The prayer circles in the air”: a qualitative study about traditional healer profiles and practice in Northern Norway

open access: yesInternational Journal of Circumpolar Health, 2018
In Northern Norway, traditional healing has been preserved by passing down the knowledge through generations. Religious prayers of healing (reading) and Sami rituals (curing) are examples of methods that are used.
Anette Langås-Larsen   +3 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

The Arctic Ocean Review Project (AOR): PHASE I REPORT 2009-2011 [PDF]

open access: yes, 2011
The Arctic Ocean Review has been organized as a project under the Protection of the Arctic Marine Environment (PAME) working group of the Arctic Council, reporting to the Senior Arctic Officials (SAOs) of the Arctic Council through PAME. Subject to the
Arctic Council, Protection of the Arctic Marine Environment (PAME)
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy