Results 71 to 80 of about 126,787,558 (294)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Arctic Oil and Gas 2007 [PDF]

open access: yes, 2008
The Arctic Councils´s report or assessment had the objective to present a holistic assessment of the environmental, social and economic, and human health impacts of current oil and gas activities in the Arctic, and to evaluate the likely course of ...
Arctic Council, Arctic Monitoring ans Assessment Programme (AMAP)
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Agreement on Cooperation on Aeronautical and Maritime Search and Rescue in the Arctic [PDF]

open access: yes, 2011
Agreement on Cooperation on Aeronautical and Maritime Search and Rescue in the Arctic - The SAR Agreement is the first legally binding agreement established under the auspices of the Arctic Council.
Arctic Council, -
core   +1 more source

A large-scale multivariate soccer athlete health, performance, and position monitoring dataset

open access: yesScientific Data
Data analysis for athletic performance optimization and injury prevention is of tremendous interest to sports teams and the scientific community. However, sports data are often sparse and hard to obtain due to legal restrictions, unwillingness to share ...
Cise Midoglu   +14 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Senior Arctic Official (SAO) Report to Ministers, Nuuk Greenland, 2011 [PDF]

open access: yes, 2011
Arctic Council Senior Arctic Officials' (SAO) Report to Ministers.
Arctic Council, -
core   +1 more source

Arctic and Sub-Arctic Bees

open access: yesNature, 1898
OF the wild bees of Alaska nothing is known, except that several species of humble-bees (Bombus) are common. Consequently, when Mr. Trevor Kincaid wrote me last year that he was going to Alaska, and would collect bees, I was expecting to see, on his return, quite a new bee-fauna.
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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