Results 81 to 90 of about 598,343 (316)
Taming the Monster Journal—A Hug to the Numerous Reviewers
Nordlit: Tidsskrift i litteratur og kultur, 2019 To you, dear reviewers: Your monstrous support was, as so often, unpaid—but valuable indeed. The energy you have put together in writing your thorough reviews substantially helped in shaping and re-shaping (and sometimes even re-re-shaping) the wonderful
Christian Beyer +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The tipping times in an Arctic sea ice system under influence of extreme events
, 2020 In light of the rapid recent retreat of Arctic sea ice, the extreme weather events triggering the variability in Arctic ice cover has drawn increasing attention.
Duan, Jinqiao +4 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
International Journal of Circumpolar Health, 2018 In Northern Norway, traditional healing has been preserved by passing down the knowledge through generations. Religious prayers of healing (reading) and Sami rituals (curing) are examples of methods that are used.
Anette Langås-Larsen +3 more
doaj +1 more source
How tropical Pacific surface cooling contributed to accelerated sea ice melt from 2007 to 2012 as ice is thinned by anthropogenic forcing [PDF]
, 2019 Over the past 40 years the Arctic sea ice minimum in September has declined. The period between 2007 and 2012 showed accelerated melt contributed to the record minima of 2007 and 2012.
Baxter, Ian
core
Geographic muting of changes in the Arctic sea ice cover [PDF]
, 2010 The seasonal cycle in Arctic sea ice extent is asymmetric. Its amplitude has grown in recent decades as the ice has retreated more rapidly in summer than in winter.
Eisenman, Ian
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
International Journal of Qualitative Studies on Health & Well-BeingBackground Chronic musculoskeletal pain (CMP) is a prevalent condition often lacking clear biomedical explanations, leading to frustration for both clinicians and patients.
Trine C. B. Andersen +3 more
doaj +1 more source
Oceanic heat advection to the Arctic in the last Millennium [PDF]
, 2011 EGU2011-8738 At present, the Arctic is responding faster to global warming than most other areas on earth, as indicated by rising air temperatures, melting glaciers and ice sheets and a decline of the sea ice cover. As part of the meridional overturning
Aagaard-Sørensen, Steffen +8 more
core