Results 71 to 80 of about 1,202,454 (306)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

THE PRINCIPLE OF THE BEST INTERESTS OF THE CHILD [PDF]

open access: yesChallenges of the Knowledge Society, 2019
Since 1919, the recognition of children's rights has begun to find an international echo, when the League of Nations ”came to life”, the name of which links to the Geneva Declaration of 1924. Adopted in 1989, by the Convention on the Rights of the Child,
Ioana PĂDURARIU
doaj  

Best Interest of the Child

open access: yesPolis, 2019
In this paper we aim to discuss the best interest of the child as one of the one of the key principles and priorities to international and domestic law. The purpose of this study is to treat the legal aspect for best interest of the child especially related to adoption institute and on the possibility of children’s adoption by homosexuals ...
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Moving Away from Certainty: Using Mediation to Avoid Unpredictable Outcomes in Relocation Disputes Involving Joint Physical Custody [PDF]

open access: yes, 2012
This Note describes the frameworks used by the courts of various states to modify joint physical custody plans when one parent wishes to relocate with the child to a different jurisdiction.
Kennedy, Brian S.
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

"For the Sake of the Children": South African Family Relocation Disputes [PDF]

open access: yesPotchefstroom Electronic Law Journal, 2011
Decisions by primary caregiving parents to relocate after divorce, thereby disrupting the non-primary caregivers’ right of contact with children or, where both parents have joint care, the denial of the other’s parental rights and responsibilities to ...
W Domingo
doaj  

Postmortem conception of a dead husband’s semen as a particular example of medically assisted procreation

open access: yesPrzegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2013
The paper covers issues concerned with the postmortem conception of a dead husband’s semen as a particular example of medically assisted procreation.
Michał Marszelewski
doaj   +1 more source

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