Results 61 to 70 of about 2,729,470 (315)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Data protection in relation to transborder information sharing for network security and criminal justice purposes [PDF]
, 2010 Between November 2012 and September 2013, Joseph A. Cannataci responded to a brief commissioned by the Directorate General of Human Rights and Rule of Law of the Council of Europe.
Cannataci, Joseph A. +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Botulism in the European Union
Eurosurveillance, 1999 Botulinum toxin was first described as a potent neurotoxin in the late eighteenth century. Currently three main distinct clinical and epidemiological botulism syndromes are described - foodborne botulism, which results from the ingestion of food ...
openaire +2 more sources
The European Union Against Social Exclusion [PDF]
, 2004 [Excerpt] Social inclusion means that people who are poor or have other problems take part in the life of society.
Inclusion Europe
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Right-to-Food: Strengthening the Legal and Political Concepts Through Soft Governance
Visegrad Journal on Bioeconomy and Sustainable Development, 2016 Addressing poverty issues in the developing world, and hunger issues in particular, is top of the global list of collective actions. However, in spite of the right-to-food commitments taken by global leaders and the international community, the problems ...
Blizkovsky Petr
doaj +1 more source
Poland’s Integration with the European Union [PDF]
, 2015 The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Błaszczyk, Maria Celina
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