Results 61 to 70 of about 796,958 (318)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A realistic bridge towards European banking union. Bruegel Policy Contribution 2013/09, June 2013 [PDF]

open access: yes, 2013
New obstacles to the European banking union have emerged over the last year, but a successful transition remains both necessary and possible. The key next step will be in the second half of 2014, when the European Central Bank (ECB) will gain supervisory
Véron, Nicolas.
core  

The candidature of Albania to the European Union. The role of the European Commission

open access: yes, 2023
reservedThis paper addresses a topic that has been widely discussed in recent years and could have an impact in the future. The topic is Albania's accession to the European Union and its potential positive and negative effects on civil society.
SULA, ALISA
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Case for a European Social Union. European Policy Brief No. 23, March 2014 [PDF]

open access: yes, 2014
This Policy Brief discusses the notion of a ‘European Social Union’, in which European countries would cooperate with an explicit social purpose. A European Social Union should not be seen as an idealistic bridge too far.
Vandenbroucke, Frank
core  

External differentiated integration : the modalities of Turkey’s opting into the European Union [PDF]

open access: yes, 2021
Turkey’s futures with the European Union has never looked so uncertain. Turkey’s relations with the European Union are at a stalemate, with accession negotiations effectively frozen.
MÜFTÜLER-BAÇ, Meltem
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The European Transformation of Modern Turkey. CEPS Paperback. September 2004 [PDF]

open access: yes, 2004
The outcome of a research project carried out by CEPS and the Economics and Foreign Policy Forum (EFPF) of Istanbul, this book examines in detail the challenges and opportunities that would arise with Turkey’s full membership of the European Union.
Ülgen, Sinan   +3 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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