Results 81 to 90 of about 2,729,470 (315)

The International Life of the European Union: Systems Theory, European Integration, and International Relations

Studia Europejskie
The research problem addressed in this thesis concerns the definition of the international life of the European Union. After a review of the positions on defining the EU itself and a review of the related approaches, the authors turn to terms associated ...
Zbigniew Czachór, Piotr Baranowski
doaj   +1 more source

"The Impact of EU's Cultural Activities on Establishing a European Identity" [PDF]

, 2000
European integration has historically been concerned with economic and commercial benefits, but now the aim is to take it further, starting with a broader base capable of involving citizens to a greater degree and strengthening the feeling of belonging ...
Kouveliotis, Kyriakos.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Small Satellites: National Regulatory Challenges

Teisė, 2019
[full article, abstract in English; abstract in Lithuanian] This article analyses the regulation of space activities, especially small satellites activities. Its purpose is to analyse the relevant international legal framework and discuss the possible
Asta Tūbaitė-Stalauskienė
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A estrutura da União Europeia

Revista Interdisciplinar de Direito, 2012
Th e structure of the European Union results from the way their systems institutional, legal and judicial systems were designed by the “founding fathers” and remained, adapted and evolved over just over half century of peace in Europe who inaugurated ...
Dora Resende Alves
doaj  

Autonomy: The Central Idea of the Reasoning of the Court of Justice

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(3), 1403-1439 | Article | (Table of Contents) I. Introduction. – II. The concept of autonomy beyond a jurisdictional claim. – III. Autonomy as a source of coherence.
Damjan Kukovec
doaj   +1 more source

The European Union Budget [PDF]

The first EU budget was drafted in 1988 under the so-called “Delors Package I.” Its budgetary headings and monetary distribution have remained unchanged until 14th July 2004, when the Commission adjusted its traditional model to a new system of headings ...
Lorca-Susino, Maria
core   +1 more source

Rewards at the top: the European Union [PDF]

, 2012
Book synopsis: Anyone observing the recent scandals in the United Kingdom could not fail to understand the political importance of the rewards of high public office.
Dimitrakopoulos, Dionyssis G., Page, E.C.   +1 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source