Results 141 to 150 of about 577,642 (264)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Enhanced intelligent train operation algorithms for metro train based on expert system and deep reinforcement learning. [PDF]

PLoS One
Huang Y, Lai W, Chen D, Lin G, Yin J.
europepmc   +1 more source

Methodology for development of an expert system to derive knowledge from existing nature-based solutions experiences. [PDF]

MethodsX, 2023
Sarabi S, Han Q, de Vries B, Romme AGL.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

DIEN Expert System Version 1 to formulate nursing diagnoses. [PDF]

Rev Cuid
Fanning Balarezo MM, Vásquez Pérez MR, Capuñay Uceda OE, Oblitas-Guerrero SM, Juárez Elera MA.   +4 more
europepmc   +1 more source

Therapy-based expert system on function and postural stability after anterior cruciate ligament reconstruction: a pilot study. [PDF]

BMC Musculoskelet Disord, 2023
Kazemnejad A, Asosheh A, Moezy A, Abasi A.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Fuzzy Expert System for Early Diagnosis of Multiple Sclerosis. [PDF]

J Biomed Phys Eng, 2022
Matinfar F, Tavakoli Golpaygani A.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Design and realization of compressor data abnormality safety monitoring and inducement traceability expert system. [PDF]

PLoS One
Wang Y, Hu S.
europepmc   +1 more source