Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The outline of the expert system for the design of experiment
The design of experiment (DoE) is a methodology originated from early 1920s when Fisher’s papers created the analysis of variance and first known experimental designs: latin squares.
Dwornicka Renata, Pietraszek Jacek
doaj +1 more source
RANCANG BANGUN APLIKASI SISTEM PAKAR UNTUK KERUSAKAN KOMPUTER DENGAN METODE BACKWARD CHAINING
he computer is a machine that can be damaged in carrying out its functions. To provide such information, it takes knowledge of a computer expert. Expert system designed as a computer program, so the expert system program can provide information like a ...
Minarni, S. Si., M.T, Rahmad Hidayat, ST
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The modifiability of rule-based expert systems [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis examines the claim that rule representations of knowledge are conveniently modified. The thesis falls into two parts and in the first, a precise
Bottaci, Leonardo
core +4 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Application Expert System of Forward Chaining and The Rule Based Reasoning For Simulation Diagnose Pest and Disease Red Onion and Chili Plant [PDF]
One of obstacles to do cultivation on red onion and chili plant is overcome pest and disease. Pest and disease attack can decrease productivity and even causes harvest fail that influence toward one of income sources the country.
Ginajar w, sasmito
core +1 more source
Expert System Approach for Manufacturability Evaluation of Nd: YAG Laser Beam Machining Process [PDF]
In this paper, an expert system (ES) is developed for manufacturability evaluation of ND:YAG laser in computer based concurrent engineering. The expert system evaluates machining cycle time and cost in less than 30 seconds.
M. Sadegh Amalnik*
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Design and Manufacturing Optimization of Abrasive Water Jet Machining using Expert System [PDF]
This paper addresses the concept of the expert system for abrasive waterjet machining. For optimization of abrasive waterjet machining, computer based concurrent engineering environment is used.
Morteza sadegh amalnik
doaj

