Results 91 to 100 of about 131,506,761 (288)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Verification of Cucumber Expert System [PDF]

open access: yes, 2003
Verification of the cucumber expert systems.
Climate Change Information Center & Renewable Energy & Expert Systems   +2 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Editorial: Human-Environmental Interactions in Prehistoric Periods – Volume II

open access: yesFrontiers in Earth Science, 2023
Guanghui Dong   +3 more
doaj   +1 more source

The Methodology of Expert Audit in the Cloud Computing System

open access: yesБезопасность информационных технологий, 2013
The problem of information security audit in the cloud computing system is discussed. The methodology of the expert audit is described, it allows to estimate not only the value of information security risk level, but also operative value of information ...
Irina Vladimirovna Mashkina   +1 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

THE ARCHITECTURE OF MULTI-COMPONENT DISTRIBUTED HYBRID EXPERT TRAINING SYSTEM

open access: yesНаукові записки Тернопільського національного педагогічного університету імені Володимира Гнатюка. Серія: Педагогіка, 2016
The paper reports on the design of a multi-component architecture of distributed hybrid expert training system that can be used for the study of knowledge base of both internal and external expert systems and artificial intelligence systems that are ...
Оleh Shevchuk
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Expert systems [PDF]

open access: yesThe Computer Journal, 1980
openaire   +1 more source

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