Results 81 to 90 of about 131,506,761 (288)

Expert system using multi-objective optimization of the direct current railway power supply system

Transport, 2018
There are many different aspects to be analyzed when designing a railway infrastructure. The energy system, which withstands the demand for energy from operating trains, must consider many factors to create a functional infrastructure, in terms of ...
Manuel Soler Nicolau, Jesús López, Santiago Tapia, José Manuel Mera   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Expert system for minimising the cost of logistic processes

Management : Journal of Contemporary Management Issues, 2002
This paper demonstrates how to use the theory of causal position in practice for evaluation, systematic design, mechanization and automation in logistic processes namely in manipulation with material.
Bohumil Hlavenka, Marek Stroner
doaj  

Conformity Assessment and Application of the Decision Rule in Acceptance or Rejecting Test Results of Drinking Water [PDF]

آب و فاضلاب
Conformity assessment of drinking water quality test results, particularly under critical water supply conditions, requires decision rules approaches that protect consumer health and prevent unjustified rejection of acceptable water sources.
Mahtab Bagheban, Noushin Sohrabnia, Fahimeh Mehranfar, Afshin Ghorban Ashrafi   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Expert system for induction motor fault detection [PDF]

Journal on Processing and Energy in Agriculture, 2010
The paper describes the development and implementation of an expert system for fault detection of induction motors. Early detection of induction motors failures may prevent the occurrence of malfunction and ensure timely replacement and servicing.
Kulić Filip, Kanović Željko, Petković Milena, Matić Dragan   +3 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

ALEES: An Agricultural Loan Evaluation Expert System

, 2001
Financial institutions such as banks have been active in the development of a variety of expert systems. Several banks have developed expert systems that capture the experience of their top loan officers in evaluating loan applications.
Bryant, Kay, K Bryant
core   +1 more source