Results 101 to 110 of about 131,506,761 (288)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2005 A Web-enabled knowledge automation expert system for formulating competitive strategies and aligned IT ...
Li, Shuliang
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Explaining and Evaluation the Efficiecny of the Strategic Decision Expert System [PDF]
مطالعات مدیریت راهبردی, 2016 This research explains and examines the decision quality, usefulness and problem solving, and accuracy and compatable components of the efficiecny of the strategic decision expert system for organizational expertise development.
Mohammad Reza Hamidizadeh
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
System and method for specifying an expert system
, 1992 A method and system are provided for specifying an expert system. Multiple task specifications are formed for specifying tasks as functional units of the expert system.
Yen, Chia H., Lee, Jonathan Y.
core +1 more source
Designing a tool/platform for developing expert systems
Taikomieji Moksliniai TyrimaiThe article analyzes the company's need to create a prototype for the development of expert systems. Expert systems and tools for their creation were examined, functions and software for the creation of an expert system that met the needs of the company ...
Donatas Daugirdas, Karolis Paliliūnas
doaj +1 more source
Expert system for voltage & VAr control
This paper proposes an expert system approach for voltage and VAr control. A decentralized control mode is used so that each area performs its proper control using only its local information.
Razanamampandry, J. +2 more
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Development of the precision feeding system for sows via a rule-based expert system
Nano ResearchCancer immunotherapy holds great promise but faces challenges in efficacy and toxicity. Nanotechnology, particularly using peptide-based drug delivery systems, offers a solution by enabling targeted delivery and controlled release. Herein, we developed a
Liyuan Peng +4 more
doaj +1 more source