Results 51 to 60 of about 223,516 (312)

Lifetime Employment and Mixed Cournot Duopoly with State-Owned and Joint-Stock Firms [PDF]

open access: yesInternational Journal of Management, Accounting and Economics, 2018
This paper examines a mixed duopoly model in which a state-owned firm competes with a joint-stock firm. The following two stages are considered. In the first stage, each firm can simultaneously and independently decide whether or not to offer lifetime ...
Kazuhiro Ohnishi
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Capital structure, business model innovation, and firm performance: Evidence from Chinese listed corporate based on system GMM model.

open access: yesPLoS ONE
This paper aims to verify the impact of capital structure on business model innovation and firm performance and the mediating effect of business model innovation.
Xu Tian, Yan Wang, Umar H A Kohar
doaj   +1 more source

Corporate Social Responsibility and Labor-Managed Duopoly with Wage Rise as Strategic Commitment [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
This paper investigates a duopoly game model in which two labor-managed firms compete in quantities. The game proceeds as follows. In the first stage, each labor-managed firm independently and simultaneously chooses the corporate social responsibility ...
Kazuhiro Ohnishi
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of ownership type and firm size on organizational culture and on the organizational culture-effectiveness linkage

open access: yesJournal of Business Economics and Management, 2013
This paper aims to extend the extant (primarily Western) organizational culture literature to emerging economies by explicitly incorporating two key contextual variables-ownership type and firm size into organizational culture model.
Kaisheng Zeng, Xiaohui Luo
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Environmental dynamism, human resource flexibility and firm performance: analysis of a multi-level causal model

open access: yes, 2010
While strategic HRM scholars have conceptualized HR flexibility as an important source of sustainable superior firm performance in dynamic environments, the process through which HR flexibility creates value for the firm has not been empirically ...
Sett, P.K., Ketkar, S.
core   +1 more source

Dynamic Model of Firm Value: Evidence from Indonesian Manufacturing Companies

open access: yesSriwijaya International Journal of Dynamic Economics and Business, 2018
This study aims to determine the factors that affect to firm value. The data used in this study is secondary data obtained from the Indonesia Stock Exchange which includes financial statements.
Kemas Muhammad Husni Thamrin   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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