Results 51 to 60 of about 128,224,258 (295)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Sub-series 2: Publications

, 2004
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core   +2 more sources

Applying the Options Framework to a Value-based Model of the Firm

Littera Scripta, 2019
This paper develops the value-based model of a firm from a conventional accounting-based approach to one that acknowledges individuals' human capital and firms' competences as fundamental creatorsof value.
Jan Vlachý
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Firm-Level, Macroeconomic, and Institutional Determinants of Firm Growth: Evidence From Europe

Economic and Business Review
To examine the main drivers of firm growth, we estimated a model integrating firm-level, industry-specific as well as country-level determinants, aiming at a comprehensive explanation of firm growth. We used a large dataset of European firms for the 2005–
Anže Burger, Andreja Jaklič, Klemen Knez, Patricia Kotnik, Matija Rojec   +4 more
doaj   +1 more source

Lifetime Employment and Mixed Cournot Duopoly with State-Owned and Joint-Stock Firms [PDF]

International Journal of Management, Accounting and Economics, 2018
This paper examines a mixed duopoly model in which a state-owned firm competes with a joint-stock firm. The following two stages are considered. In the first stage, each firm can simultaneously and independently decide whether or not to offer lifetime ...
Kazuhiro Ohnishi
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Capital structure, business model innovation, and firm performance: Evidence from Chinese listed corporate based on system GMM model.

PLoS ONE
This paper aims to verify the impact of capital structure on business model innovation and firm performance and the mediating effect of business model innovation.
Xu Tian, Yan Wang, Umar H A Kohar
doaj   +1 more source

How do digital capabilities affect firm performance? The mediating role of technological capabilities in the “new normal”

Journal of Innovation & Knowledge, 2022
This study proposes a model to explain the effect of digital capabilities on firm performance in the “new normal” context from a firm-level perspective.
Jorge Heredia, Mauricio Castillo-Vergara, Cristian Geldes, Felix M. Carbajal Gamarra, Alejandro Flores, Walter Heredia   +5 more
doaj   +1 more source