Results 91 to 100 of about 128,360,030 (297)

The Court of Justice of the European Union as a fundamental rights tribunal: challenges for the effective delivery of fundamental rights in the area of freedom, security and justice. CEPS Paper in Liberty and Security in Europe No. 49, 29 August 2012 [PDF]

open access: yes, 2012
This paper reflects on the challenges facing the effective implementation of the new EU fundamental rights architecture that emerged from the Lisbon Treaty. Particular attention is paid to the role of the Court of Justice of the European Union (CJEU) and
Petkova, Bilyana   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Embedding Fundamental Aspects of the Relational Blockworld Interpretation in Geometric (or Clifford) Algebra [PDF]

open access: yes, 2007
I summarize Silberstein, et. al’s (2006) discussion of the derivation of the Heisenberg commutators, whose work is based on Kaiser (1981, 1990) and Bohr, et. al. (1995, 2004a,b).
William M Kallfelz, Kallfelz, William
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Smarandache Function [PDF]

open access: yes, 1996
The function named in the title of this book is originated from the exiled Romanian mathematician Florentin Smarandache, who has significant contributions not only in mathematics, but also in literature.
Seleacu, V.   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Different Variants of Fundamental Portfolio

open access: yesFolia Oeconomica Stetinensia, 2014
The paper proposes the fundamental portfolio of securities. This portfolio is an alternative for the classic Markowitz model, which combines fundamental analysis with portfolio analysis.
Tarczyński Waldemar
doaj   +1 more source

On the Brauer-Manin obstruction for degree-four del Pezzo surfaces [PDF]

open access: yes, 2016
We show that for every integer 1≤d≤4 and every finite set S of places, there exists a degree-d del Pezzo surface X over Q such that Br(X)/Br(Q)≅Z/2Z and the nontrivial Brauer class has a nonconstant local evaluation exactly at the places in S.
Fundamental mathematics   +3 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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