Results 121 to 130 of about 128,360,030 (297)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Applications of Surface Correlation to the Estimation of the Harmonic Fundamental of Speech
We present a method for estimating the fundamental frequency of harmonic signals, and apply this method to human speech. The method is based on cross-spectral methods, which provide accurate resolution of multicomponent FM signals in both time and ...
Nelson Douglas J
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Schur line defect correlators and giant graviton expansion
We consider Schur line defect correlators in four dimensional N $$ \mathcal{N} $$ = 4 U(N) SYM and their giant graviton expansion encoding finite N corrections to the large N limit.
M. Beccaria
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Mittag-Leffler function, often referred to as the ”queen function” of fractional calculus, plays a fundamental role in solving fractional differential equations across various disciplines, including physics and engineering.
Ahmed Bakhet +3 more
doaj +1 more source
Franet National contribution to the Fundamental Rights Report 2025: Portugal
Disclaimer: This document was commissioned under contract as background material for a comparative analysis by the European Union Agency for Fundamental Rights (FRA) for the project ‘FRA Fundamental Rights Report 2025’.
Henriques, Marina +2 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Genetic analyses, which examine the phenotypic effects of mutations both individually and in combination, have been fundamental to our understanding of cellular functions.
Lucas Fuentes Valenzuela +2 more
doaj +1 more source

