Results 111 to 120 of about 1,972,647 (310)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

THE BASIC LINES OF COOPERATION BETWEEN THE DEPARTMENT OF PHILOLOGY AND HISTORY AT ANZHERO-SUDZHENSK BRANCH OF KEMEROVO STATE UNIVERSITY AND GENERAL EDUCATION INSTITUTIONS OF ANZHERO-SUDZHENSK AND THE NORTH OF KUZBASS

open access: yesВестник Кемеровского государственного университета, 2013
The paper addresses the basic lines of cooperation between the Department of Philology and History at AnzheroSudzhensk branch of Kemerovo State University and general education institutions in Anzhero-Sudzhensk and the North of Kuzbass.
E. N. Lisitskaya, T. L. Volchkova
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Reflexões sobre impostos e Raison d’État

open access: yesRevista de Economia Mackenzie, 2004
The aim of the article is some common presuppositions, in modern history, of the ecclesiastical institutions as well as the State as the basis for the contro l and extraction of economic re s o u rces through the knowledge, the most accurate possible,
Roberto Romano
doaj  

Waqf system and civil society: A reading of the implications and limits of the relationship and the developmental function

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية
The relationship between religion and politics is one of the most important obstacles to political and economic stability in the Arab world. after adopting the option of nationalism as an ideology and political approach after the first and second Arab ...
Mohamed TAIEB AMOUR, DELLALI Djilali
doaj   +1 more source

Supplementary Pension Funds in Hungary [PDF]

open access: yes
Hungary has about ten years history of pension privatization process and the Hungarian experience could be really instructive. This paper is focused on the supplementary pensions trying to prove that no kind of reform of state pension system is able to ...
Matits, Agnes
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

O conselho naval no oitocentos: propostas para o estudo da relação entre civis e militares no Império [PDF]

open access: yesNavigator, 2010
This essay aims to propose some reflections about the possibilities of study on the military and military institutions from the social history. Using the Naval Council, an advisory body created in the organizational structure of the Secretariat of State ...
Renato Jorge Paranhos Restier Junior
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Los individuos como elemento de análisis histórico en la temática del estado soberano de Santander

open access: yesCambios y Permanencias, 2010
The panorama of the investigations on the conformation of the Sovereign State of Santander shows a predominance of problems focused in the institutions, the laws, the civil wars, the political agendas.
Lina Constanza Díaz Boada
doaj  

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