Results 101 to 110 of about 134,904 (302)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Top-Down Processing: A Network Analysis of The Lord of the Rings as a Means of Defining Good and Evil

open access: yesSpectrum, 2018
This essay was written for Dr. Quamen’s ENGL 486 class on the Internet as Environment. Using network theory, I seek to analyze the structural characteristics of power and authority in J.R.R. Tolkien’s The Lord of the Rings.
Dennis John Werbicki
doaj   +1 more source

Особенности образов зла в творчестве Дж.Р.Р. Толкина [PDF]

open access: yes, 2014
DISTINCTIVE FEATURES OF NEGATIVE CHARACTERS IN J.R.R. TOLKIEN’S “THE LORD OF THE RINGS”. О. VALOVENРассматриваются образы зла в трилогии "Властелин колец" известного английского писателя, филолога, ученого-медиевиста, оксфордского профессора Джона ...
Валовень, О. Н.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

El espacio narrativo en El Señor de los Anillos. [PDF]

open access: yes, 2009
The work consists of an analysis of the narrative space in the trilogy The Lord of the Rings, by J.R.R. Tolkien. The analysis was carried out by dividing the space into three levels: location, scope of performance, and spatial configuration. Examples and
Galera González, Sergio
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Vegetal Modes of Resistance: Arboreal Eco-Rebellion in The Lord of the Rings

open access: yesHumanities
This article posits that a fictional eco-rebel might be not just a human (child or young adult), but also a plant, revolting against the destruction of its dwelling place. The argument is furthered by way of a literary analysis of arboreal agency in J. R.
Lykke Guanio-Uluru
doaj   +1 more source

The universe of the quasi-realia of the novel “The lord of the rings” by J. R. R. Tolkien [PDF]

open access: yes, 2015
В статье рассматривается пространство квазиреалий романа Дж. Р.Р. Толкина «Властелин Колец», исследуются исторические и этимологические корни квазиреалий в нём, а также анализируются классификации квазиреалий романа и предлагается свой вариант ...
Bozhko, E. M., Божко, Е. М.
core  

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