Results 101 to 110 of about 5,136 (295)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Top-Down Processing: A Network Analysis of The Lord of the Rings as a Means of Defining Good and Evil

open access: yesSpectrum, 2018
This essay was written for Dr. Quamen’s ENGL 486 class on the Internet as Environment. Using network theory, I seek to analyze the structural characteristics of power and authority in J.R.R. Tolkien’s The Lord of the Rings.
Dennis John Werbicki
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Shadow of the Past. The Lord of the Rings and the Gothic Novel [PDF]

open access: yes, 2016
The present paper is devoted to the question of the past in J.R.R. Tolkien’s The Lord of the Rings in reference to the Gothic Novel and the way it approaches this subject.
Ferdynus, Katarzyna, Katarzyna Ferdynus
core   +2 more sources

WAYS OF TRANSLATING METAPHORS IN J.R.R.TOLKIEN’S “THE LORD OF THE RINGS”

open access: yesStudia Universitatis Moldaviae: Stiinte Umanistice, 2008
Articolul prezent este dedicat studiului contrastiv al traducerii metaforei de către doi translatori V.Muraviov şi V.Motorina în romanul lui J.R.R.Tolkien “Regele inelelor”.
USM ADMIN
doaj  

Naming, Order and Power: She Unnames Them All of Ursula & Lord of the Rings of Tolkien

open access: yesİstanbul Hukuk Mecmuası
One of the two points that establishes a relationship between law and literature is the legal themes in literary works, and the other is the literary character of law itself.
O. Vahdet İşsevenler
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Lord of the Peach Rings [PDF]

open access: yes, 2009
The Lord of the Peach Rings was an entry in Myrin Library\u27s 5th Annual Edible Books Festival at Ursinus College.https://digitalcommons.ursinus.edu/ebf/1150/thumbnail ...
Sakmann, Lindsay
core  

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