Results 121 to 130 of about 134,904 (302)

Book-Review: The Sweet and the Bitter: Death and Dying in J. R. R. Tolkien’s The Lord of the Rings

open access: yesFafnir, 2018
Amendt-Raduege, Amy. The Sweet and the Bitter: Death and Dying in J. R. R. Tolkien’s The Lord of the Rings. Kent State UP, 2017. ISBN 978-1606353059.
Nicholas Dalbey
doaj  

Sponsorship [PDF]

open access: yes, 2011
LOCOG, headed by the charismatic Lord Sebastian Coe, have raised £600m in sponsorship revenue from 26 corporate backers for the London 2012 Games. No doubt, corporations are still seduced by the opportunity to bask in the reflected glory of the Gold ...
Elesa Argent
core   +1 more source

The lord of the rings [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2017
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tolkien Among the Moderns (2015), ed. by Ralph C. Wood [PDF]

open access: yes, 2018
Book review by Robin Anne Reid of Tolkien Among the Moderns (2015) ed.
Reid, Robin A., Dr.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Prominence of Pippin [PDF]

open access: yes, 2015
When building a fictional world as involved and vast as that of J.R.R. Tolkien’s multiple drafts are a must in order to work out the exact details and to make sure that all the possible loose ends are tied up and addressed.
Sunderlage, Jasmine
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Onomastique et passion des mots chez J.R.R. Tolkien : Sources et fondations de son ‘légendaire’ [PDF]

open access: yes, 2010
J.R.R. Tolkien is best known as the author of The Lord of the Rings. He was also Merton Professor of English language and literature at Oxford University, and a respected philologist whose passion for words and languages fueled his building of the ...
A. Birks, Y. Le Boulicaut
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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