Results 141 to 150 of about 3,613,732 (315)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Sālmand, 2016 Objectives: The present study aimed to examine the life meaningfulness among the elderly people living in nursing homes of Isfahan, Iran based on their perceived social support from 3 sources of family, friends, and significant others. Methods &
Atefe Ahmadi +4 more
doaj
EVOLUTION AND THE MEANING OF LIFE
Zygon, 1987 . The last century has witnessed a succession of revolutionary transformations in the discipline of biology. However, the rapid expansion of our understanding of life and its nature has had curiously little impact on the way that questions about life ...
doaj +2 more sources
Religiousness, Spirituality, and Meaning in Life in Depression [PDF]
, 2021 Nyamat Chadha, Shoma Chakrawarty
openalex +1 more source
Using appreciative inquiry to explore the professional practice of a lecturer in higher education: moving towards life-centric practice [PDF]
, 2010 This paper reports on a strategy for exploring the life-centric practice of a lecturer in Higher Education. The initiative for this inquiry arose out of the realisation that there did not appear to be positive, heart-lifting stories in a lecturer’s ...
Giles, David, Kung, Susie
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Logos: Revista de Lingüística, Literatura y FilosofíaEl artículo intenta sistematizar los enfoques existentes sobre el problema del sentido de la vida humana. En el marco de la conocida división en nihilismo, sobrenaturalismo y naturalismo, se lleva a cabo un análisis del sentido, que se ilustra con el ...
Sergey Aleksandrovich Lokhov +1 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source