Results 41 to 50 of about 761 (248)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Design and Analysis of a Decoupling Algorithm Based on a Generalized Mathematical Model of MMAB Converters

open access: yesMathematics
This paper presents the mathematical modeling, numerical implementation, and experimental validation of a decoupling control algorithm for a five-port multiport modular active bridge (MMAB) converter in DC microgrid applications. Based on an analytically
Milan Lacko   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Model-Based Mitigation of Low-Order Harmonics in Overmodulated SynRM Drives Considering Cross-Saturation

open access: yesIEEE Access
Operation of electric drives in the overmodulation region and six-step can optimize switching losses and increase the utilization of the dc-link voltage, but inevitably introduces low-order voltage harmonics that appear as current distortions in the ...
Petr Zakopal, Ondrej Lipcak, Jan Bauer
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Performance Optimization of Synchronous Reluctance Motor using Adaptive MTPA Curve Fitting with Anti-Windup Current Control

open access: yesResults in Engineering
Synchronous Reluctance Motors have gained increasing attention in modern electric drive applications due to their high efficiency, robustness, and magnet-free rotor design.
Alex V, Rammohan A
doaj   +1 more source

A Motion Separation Method for the Control of Induction Motors with Prescribed Closed-Loop Dynamics

open access: yesIFAC Proceedings Volumes, 1995
Abstract A new method of induction motor drive control without shaft sensors is presented suited especially to applications requiring prescribed closed-loop dynamics. Only the stator currents are measured. The system is self exciting, automatically generating its own polyphase currents and achieves high torque efficiency.
S.J. Dodds, V.A. Utkin, J. Vittek
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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