Results 61 to 70 of about 127,549,073 (315)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Turkey's 'Return' to the Middle East
, 2014 Turkey’s potential as a regional power in the Middle East has been discussed since the 1990s. This was in contrast with Turkey’s historical reluctance to get deeply involved with this region.
Altunışık, Meliha
core +1 more source
Generative AI-driven sensor fusion for missing-modality and open-set smartphone activity recognition
Discover ComputingSmartphone-based Human Activity Recognition (HAR) is increasingly used in Internet of Things (IoT) and edge-intelligence applications for health monitoring, context-aware services, and mobile sensing.
Ahmed Shdefat +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Non-Prosthetic Assistive Technologies for Persons with Hearing Losses: A Survey
TechnologiesMillions of persons worldwide experience varying degrees of hearing loss, traditionally addressed through prosthetic solutions such as hearing aids and cochlear implants.
Reemas Alsubaiei +9 more
doaj +1 more source
ANTITHROMBOTIC PROPHYLAXIS IN THE MIDDLE EAST
Mediterranean Journal of Hematology and Infectious Diseases, 2011 Several factors have been proposed to explain the persistence of a high incidence of venous thromboembolism worldwide with its associated morbidity and mortality. Underutilization of anticoagulants and failure of adherence to thromboprophylaxis guidelines are emerging global health concerns.
Samir Arnaout +5 more
openaire +4 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The Rubik Cube of the Wider Middle East. CEPS Paperback. February 2003 [PDF]
, 2003 Given the complexity and severity of the problems involved, this book asserts that a comprehensive regional initiative for the Wider Middle East is called for and proceeds to outline exactly what that would entail.
Emerson, Michael, Tocci, Nathalie
core