Results 41 to 50 of about 127,549,073 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied Sciences, 2022 This paper presents the concept and design of a system that embeds piezoelectric sensors to measure the voltage of a mechanical load applied to it. COMSOL Multiphysics, a finite element simulation tool, was used to design the system and analyze the data ...
Bachar Mourched +8 more
doaj +1 more source
Health in the Middle East [PDF]
BMJ, 2006 At the height of the Arab-Islamic civilisation between the 8th and 12th century, scholars laid the foundation for modern medicine based on observation and reasoning.1 Avicenna's Al Qanun of Medicine was the standard medical text in Europe for several centuries. In the bimaristans (hospitals), still standing in the heart of Aleppo (figure), the mentally
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Megalithism in the Middle East
, 2022 Seven thousand years ago, the Middle East witnessed the emergence of new funerary rites. Previous traditions of burying the dead directly in the earth, in jars, or in an ossuary, were replaced with a new practice of inhumation inside megalithic tombs.
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Gels, 2023 Water scarcity is a growing global issue, particularly in areas with limited freshwater sources, urging for sustainable water management practices to insure equitable access for all people. One way to address this problem is to implement advanced methods
Khaled Younes +8 more
doaj +1 more source
Middle East Respiratory Syndrome [PDF]
New England Journal of Medicine, 2017 The Middle East respiratory syndrome is caused by a coronavirus that was first identified in Saudi Arabia in 2012. Periodic outbreaks continue to occur in the Middle East and elsewhere. This report provides the latest information on MERS.
Arabi, Yaseen M. +15 more
openaire +3 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Journal of King Saud University: Engineering SciencesThe rising demand for low-cost, sustainable construction materials has intensified interest in repurposing agricultural waste fibers for cementitious applications. This study investigates the viability of using untreated date palm fibers (DPFs), a widely
Raghed AlSehali +5 more
doaj +1 more source