Results 41 to 50 of about 443,044 (269)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Exploiting heart rate variability for driver drowsiness detection using wearable sensors and machine learning

Scientific Reports
Driver drowsiness is a critical issue in transportation systems and a leading cause of traffic accidents. Common factors contributing to accidents include intoxicated driving, fatigue, and sleep deprivation.
Zakwan AlArnaout, Chamseddine Zaki, Yehia Kotb, Mouhammad AlAkkoumi, Nour Mostafa   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Application of Unsupervised Machine Learning for the Evaluation of Aerogels’ Efficiency towards Ion Removal—A Principal Component Analysis (PCA) Approach

Gels, 2023
Water scarcity is a global problem affecting millions of people. It can lead to severe economic, social, and environmental consequences. It can also have several impacts on agriculture, industry, and households, leading to a decrease in human quality of ...
Khaled Younes, Yahya Kharboutly, Mayssara Antar, Hamdi Chaouk, Emil Obeid, Omar Mouhtady, Mahmoud Abu-samha, Jalal Halwani, Nimer Murshid   +8 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Generative AI-driven sensor fusion for missing-modality and open-set smartphone activity recognition

Discover Computing
Smartphone-based Human Activity Recognition (HAR) is increasingly used in Internet of Things (IoT) and edge-intelligence applications for health monitoring, context-aware services, and mobile sensing.
Ahmed Shdefat, Julien El-Amine, Ersin Elbasi, Fahmi El-Sayed, Nour Moustafa   +4 more
doaj   +1 more source

3D SPH-FEM MODELLING OF MICRO MILLING OF Ti-6Al-4V

Journal of Advances in Manufacturing Engineering, 2022
Modelling of micro milling process is still one of the most challenging research topics. This paper presents a new 3D SPH-FEM technique used to model micro end milling operation of titanium alloy.
Murat Demiral, Ali Mamedov
doaj  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Utilizing Dry Electrode Electroencephalography and AI Robotics for Cognitive Stress Monitoring in Video Gaming

Applied System Innovation
This research explores the integration of the Dry Sensor Interface-24 (DSI-24) EEG headset with a ChatGPT-enabled Furhat robot to monitor cognitive stress in video gaming environments.
Aseel A. Alrasheedi, Alyah Z. Alrabeah, Fatemah J. Almuhareb, Noureyah M. Y. Alras, Shaymaa N. Alduaij, Abdullah S. Karar, Sherif Said, Karim Youssef, Samer Al Kork   +8 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source