Results 191 to 200 of about 173,239 (326)

When the Milky Way hosted a quasar

, 2022
Marin F, Churazov E, Khabibullin I, Ferrazzoli R, Gesu LD, Barnouin T, Marco AD, Middei R, Vikhlinin A, Costa E, Soffitta P, Muleri F, Sunyaev R, Forman W, Kraft R, Bianchi S, Donnarumma I, Petrucci P, Enoto T, Agudo I, Antonelli L, Bachetti M, Baldini L, Baumgartner W, Bellazzini R, Bongiorno S, Bonino R, Brez A, Bucciantini N, Capitanio F, Castellano S, Cavazzuti E, Chen C, Ciprini S, De Rosa A, Monte ED, Lalla ND, Doroshenko V, Dovciak M, Ehlert S, Evangelista Y, Fabiani S, Garcia J, Gunji S, Hayashida K, Heyl J, Ingram A, Iwakiri W, Jorstad S, Kaaret P, Karas V, Kitaguchi T, Kolodziejczak J, Krawczynski H, Monaca FL, Latronico L, Liodakis I, Maldera S, Manfreda A, Marinucci A, Marscher A, Marshall H, Massaro F, Matt G, Mitsuishi I, Mizuno T, Negro M, Ng C, O'Dell S, Omodei N, Oppedisano C, Papitto A, Pavlov G, Peirson A, Perri M, Pesce-Rollins M, Pilia M, Possenti A, Poutanen J, Puccetti S, Ramsey B, Rankin J, Ratheesh A, Roberts O, Romani R, Sgro C, Slane P, Spandre G, Swartz D, Tamagawa T, Tavecchio F, Taverna R, Tawara Y, Tennant A, Thomas N, Tombesi F, Trois A, Tsygankov S, Turolla R, Vink J, Weisskopf M, Wu K, Xie F, Zane S.   +103 more
europepmc   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Discovery of a high-velocity cloud of the Milky Way as a potential dark galaxy. [PDF]

Sci Adv
Liu XL, Xu JL, Jiang P, Zhu M, Zhang CP, Yu N, Xu Y, Guan X, Wang JJ.   +8 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

A Deep Learning Biomimetic Milky Way Compass. [PDF]

Biomimetics (Basel)
Tao Y, Lucas M, Perera A, Teague S, McIntyre T, Ogunwa T, Warrant E, Chahl J.   +7 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Author Correction: Comparison of a new type of Dark Matter with the Milky Way and M31 grand rotation curves. [PDF]

Sci Rep
Law BM.
europepmc   +1 more source

Across the Pons and to the Milky Way: Where Are the Neuroradiology Publications? [PDF]

AJNR Am J Neuroradiol, 2019
Lehman VT.
europepmc   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Comparison of a new type of Dark Matter with the Milky Way and M31 grand rotation curves. [PDF]

Sci Rep
Law BM.
europepmc   +1 more source