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Chemical Evolution of the Milky Way and Chemical Tagging [PDF]
, 2022 One of the most important unsolved mysteries of astronomy is the formation and evolution of galaxies. The Milky Way is an ideal testbed for testing our understanding of galaxy evolution, as we can directly observe individual stars and their properties ...Chen, Boquancore QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
Advanced Science, EarlyView.The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez +8 morewiley +1 more sourceSloan Digital Sky Survey. V. Pioneering Panoptic Spectroscopy
The Astronomical JournalThe Sloan Digital Sky Survey V (SDSS-V) is pioneering panoptic spectroscopy: it is the first all-sky, multiepoch, optical-to-infrared spectroscopic survey.Juna A. Kollmeier, Hans-Walter Rix, Conny Aerts, James Aird, Pablo Vera Alfaro, Andrés Almeida, Scott F. Anderson, Stefan M. Arseneau, Roberto J. Assef, Shir Aviram, Catarina Aydar, Carles Badenes, Avrajit Bandyopadhyay, Kat Barger, Robert H. Barkhouser, Franz E. Bauer, Aida Behmard, Chad Bender, Felipe Besser, Binod Bhattarai, Pavaman Bilgi, Jonathan Bird, Dmitry Bizyaev, Guillermo A. Blanc, Michael R. Blanton, John Bochanski, Jo Bovy, Christopher Brandon, William Nielsen Brandt, Joel R. Brownstein, Johannes Buchner, Joseph N. Burchett, Joleen Carlberg, Andrew R. Casey, Lesly Castaneda-Carlos, Priyanka Chakraborty, Julio Chanamé, Vedant Chandra, Brian Cherinka, Igor Chilingarian, Johan Comparat, Maren Cosens, Kevin Covey, Jeffrey D. Crane, Nicole R. Crumpler, Irene Cruz-Gonzalez, Katia Cunha, Tim Cunningham, Xinyu Dai, Jeremy Darling, James W. Davidson Jr., Megan C. Davis, Nathan De Lee, Niall Deacon, José Eduardo Méndez Delgado, Sebastian Demasi, Mariia Demianenko, Mark Derwent, Elena D’Onghia, Francesco Di Mille, Bruno Dias, John Donor, Peter N. Dow, Niv Drory, Tom Dwelly, Oleg Egorov, Evgeniya Egorova, Kareem El-Badry, Mike Engelman, Mike Eracleous, Xiaohui Fan, Emily Farr, Logan Fries, Peter Frinchaboy, Cynthia S. Froning, Boris T. Gänsicke, Pablo García, Joseph Gelfand, Nicola Pietro Gentile Fusillo, Simon Glover, Katie Grabowski, Eva K. Grebel, Paul J. Green, Catherine Grier, Pramod Gupta, Aidan C. Gray, Maximilian Häberle, Patrick B. Hall, Randolph P. Hammond, Keith Hawkins, Albert C. Harding, Viola Hegedűs, Tom Herbst, J. J. Hermes, Paola Rodríguez Hidalgo, Thomas Hilder, David W Hogg, Jon A. Holtzman, Danny Horta, Yang Huang, Hsiang-Chih Hwang, Hector Javier Ibarra-Medel, Julie Imig, Keith Inight, Arghajit Jana, Alexander P. Ji, Óscar Jiménez-Arranz, Paula Jofre, Matt Johns, Jennifer Johnson, James W. Johnson, Evelyn J. Johnston, Amy M Jones, Ivan Katkov, Gillian R. Knapp, Anton M. Koekemoer, Marina Kounkel, Kathryn Kreckel, Dhanesh Krishnarao, Mirko Krumpe, Nimisha Kumari, Thomas Kupfer, Ivan Lacerna, Chervin Laporte, Sebastien Lepine, Jing Li, Xin Liu, Sarah Loebman, Knox Long, Alexandre Roman-Lopes, Yuxi Lu, Steven Raymond Majewski, Dan Maoz, Kevin A. McKinnon, Ilija Medan, Andrea Merloni, Dante Minniti, Sean Morrison, Natalie Myers, Szabolcs Mészáros, Kirpal Nandra, Prasanta K. Nayak, Melissa K. Ness, David L. Nidever, Thomas O’Brien, Micah Oeur, Audrey Oravetz, Daniel Oravetz, Jonah Otto, Gautham Adamane Pallathadka, Povilas Palunas, Kaike Pan, Daniel Pappalardo, Rakesh Pandey, Castalia Alenka Negrete Peñaloza, Marc H. Pinsonneault, Richard W. Pogge, Manuchehr Taghizadeh Popp, Adrian M. Price-Whelan, Nadiia Pulatova, Dan Qiu, Solange Ramirez, Amy Rankine, Claudio Ricci, Jessie C. Runnoe, Sebastian Sanchez, Mara Salvato, Sumit K. Sarbadhicary, Natascha Sattler, Andrew K. Saydjari, Conor Sayres, Eva Schinnerer, Kevin C. Schlaufman, Donald P. Schneider, Matthias R. Schreiber, Axel Schwope, Javier Serna, Yue Shen, Cristóbal Sifón, Amrita Singh, Amaya Sinha, Stephen Smee, Ying-Yi Song, Diogo Souto, Keivan G. Stassun, Matthias Steinmetz, Alexander Stone-Martinez, Guy Stringfellow, Amelia Stutz, José Sánchez-Gallego, Jonathan C. Tan, Jamie Tayar, Riley Thai, Ani Thakar, Yuan-Sen Ting, Andrew Tkachenko, Gagik Tovmassian, Benny Trakhtenbrot, José G. Fernández-Trincado, Nicholas Troup, Jonathan Trump, Sarah Tuttle, Roeland P. van der Marel, Sandro Villanova, Jaime Villaseñor, Stefanie Wachter, Zachary Way, Anne-Marie Weijmans, David Weinberg, Adam Wheeler, Alessa I. Wiggins, John Wilson, Aida Wofford, Tony Wong, Qiaoya Wu, Dominika Wylezalek, Rosemary F. G. Wyse, Xiang-Xiang Xue, Qian Yang, Jason Ybarra, Nadia Zakamska, Eleonora Zari, Gail Zasowski, Grisha Zeltyn, Catherine Zucker, Carlos G. Román-Zúñiga, Rodolfo de J. Zermeño +226 moredoaj +1 more sourceAnalysis of Planetary Nebulae in the Milky Way: Physical Properties, Chemical Abundances, and Galactic Distributions
In this study, we investigate the physical and chemical properties of planetary nebulae (PNe) from the Milky Way Galaxy using the largest number of sources to date, with 1,449 True PNe from the HASH database. Among the Galactic components thin disk, thick disk, halo, and bulge-most PNe are concentrated in the Galactic disk, with a median angular size ...Erzincan, N., Aksaker, N., Akyuz, A., Parker, Q. +3 moreopenaire +2 more sourcesObservational evidence for the accretion of low-metallicity gas onto the Milky Way; metallicity, physical conditions and distance limit for HVC complex C
, 1998 13 pages; LaTeX; to be published in: Proceedings of the High-Velocity Cloud workshop, eds. B.K. Gibson, T.S. Axelrod and M.E. Putman (ASP Conf. Ser.)Wakker, Bart P., Howk, J. Chris, Savage, Bart D., Tufte, Steve L., Reynolds, Ron J., van Woerden, Hugo, Schwarz, Ulrich J., Peletier, Reynier F. +7 moreopenaire +3 more sourcesPerivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker +17 morewiley +1 more sourceLC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization
Advanced Science, EarlyView.SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang +17 morewiley +1 more source
