Results 91 to 100 of about 132,101,555 (310)

Priapism — A New Approach to Management [PDF]

Proceedings of the Royal Society of Medicine, 1968
W R, Bell, W R, Pitney
openaire   +2 more sources

Wetlands of New Jersey:

A presentation by Ruth McCabe on the New Jersey wetlands in March 1972, with a particular focus on the Wetlands Act passed in ...
McCabe, Ruth
core   +1 more source

New Jersey Floodplain News: Issue 4

, 2008
New Jersey Association for Floodplain Management (NJAFM) is dedicated to reducing loss of life and property damage resulting from floods and promoting sound floodplain management at all levels of government. This issue of NJAFM's newsletter features the

core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Management of insomnia: update and new approaches

Nature and Science of Sleep, 2010
Insomnia is the most prevalent sleep disorder worldwide. A number of studies evaluated the efficacy of pharmacological and nonpharmacological treatment approaches. To obtain long-term effects in the management of chronic insomnia, cognitive-behavioral therapy for insomnia (CBT-I) is the treatment of first choice, encompassing education about sleep and ...
Thomas, Unbehaun, Kai, Spiegelhalder, Verena, Hirscher, Dieter, Riemann   +3 more
openaire   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A collaborative approach to design and delivery of a flipped classroom : a cross cultural management experience

, 2016
This paper explores a collaborative approach to the ongoing process of developing and delivering a flipped classroom teaching and learning design in an undergraduate cross cultural management unit in a Business Degree.
Kippist, Louise (R13516), Macmullen, Paul (R18971)   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A NEW APPROACH TO THE ASSESSMENT OF EFFECTIVE MANAGEMENT OF GAS SUPPLY DIVERSIFICATION

Baltic Journal of Economic Studies, 2017
The purpose of the paper is to study the current state and trends in the development of the basic indicators of the EU gas sector, to generalize the theoretical and methodological approaches to calculating the gas diversification factor, assess and ...
Oleh Dzoba, Liliya Marynchak, Oleksandra Romashko   +2 more
doaj  

Genetic structure and historic demography of endangered unarmoured threespine stickleback at southern latitudes signals a potential new management approach. [PDF]

Mol Ecol, 2022
Turba R, Richmond JQ, Fitz-Gibbon S, Morselli M, Fisher RN, Swift CC, Ruiz-Campos G, Backlin AR, Dellith C, Jacobs DK.   +9 more
europepmc   +1 more source