Results 61 to 70 of about 132,804 (307)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Intraocular lens power calculation in eyes with short axial length

Indian Journal of Ophthalmology, 2014
Aim: To evaluate and compare the predictive capacity of four intraocular lens (IOL) power calculation formulas (SRK/T, Hoffer Q, Holladay 1, and Haigis) in eyes shorter than 22.0 mm. Setting and Design: Observational study.
Marilita M Moschos, Irini P Chatziralli, Chryssanthi Koutsandrea   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Bilateral monosymptomatic optic neuritis following Mycoplasma pneumoniae infection: A case report and literature review

Indian Journal of Ophthalmology, 2014
Herein, we report the clinical findings, treatment choice, and clinical course of a rare case of Mycoplasma pneumoniae (M. pneumoniae) infection with the sole manifestation of optic neuritis (ON).
Wei-Yu Chiang, Hsiu-Mei Huang
doaj   +1 more source

Teratogenic test of Pandanus conoideus var. yellow fruit extract to development of rat embryo (Rattus norvegicus) [PDF]

, 2010
Muna L, Astirin OP, Sugiyarto. 2010. Uji teratogenik ekstrak Pandanus conoideus varietas buah kuning terhadap perkembangan embrio tikus putih (Rattus norvegicus). Nusantara Bioscience 2: 126-134.
ASTIRIN, OKID PARAMA, MUNA, LINTAL, SUGIYARTO,   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effects of gamma radiation on fetal development in mice [PDF]

Iranian Journal of Reproductive Medicine, 2016
Background: Many cancer patients receive radiotherapy which may lead to serious damages to the ovary storage and the matrix muscle state. Some of these patients may admit to infertility clinics for having pregnancy and on the other hand hormonal ...
Tahere Dehghan, Hossein Mozdarani, Arezoo Khoradmehr, Seyed Mehdi Kalantar   +3 more
doaj  

A simple modification of the Farnsworth-Munsell 100-Hue test for much faster assessment of color vision

Indian Journal of Ophthalmology, 2014
Purpose: The Farnsworth-Munsell (FM) 100-hue test is well known but is also time consuming, especially its analytical component. To reduce this needless time-waste during precious working hours, a simple modification was devised.
Supriyo Ghose, Dinesh Shrey, Pradeep Venkatesh, Twinkle Parmar, Sourabh Sharma   +4 more
doaj   +1 more source

OP15.08: Influence of the initial and final number of fetuses after multifetal pregnancy reduction on successful pregnancy outcome [PDF]

Ultrasound in Obstetrics & Gynecology, 2007
fetal anomalies present postnatally corresponded very closely to those diagnosed prenatally. At 6 hours of life one of the conjoined twins had worsening congestive heart failure and at day 3 of life a successful urgent separation occurred for the pump twin while the anomalous acardiac twin expired. The pump twin continues to do well today but will need
I. E. Timor‐Tritsch, M. Kudla, C. Lee, A. Monteagudo, A. Bashiri, A. Arslan   +5 more
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source