Results 1 to 10 of about 134,171,610 (311)

Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions [PDF]

Journal of Pharmaceutical Health Care and Sciences, 2020
Background Generic drugs are heavily promoted in Japan. The aim of this retrospective single-center study was to clarify whether the frequency and reason that patients request a switch from a generic drug to the original drug differ according to ...
Yuhei Hamada, Masashi Uchida, Sayaka Arai, Kaori Yamazaki, Mariko Takeda, Kenichi Arai, Takako Nakamura, Takaaki Suzuki, Itsuko Ishii   +8 more
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The problem of choice: original drug or generic? Emphasis on rosuvastatin

Рациональная фармакотерапия в кардиологии, 2022
An increase in the life expectancy of the population and the number of polymorbid patients with a combination of two or more diseases in different age categories, including among young people, has led to a significant increase in the cost of medical care
O. A. Polyakova, O. D. Ostroumova
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Pharmacokinetic parameters, safety and drug-drug interactions of mirtazapine and tizanidine, combined in the new original drug Dorsumio®

Неврология, нейропсихиатрия, психосоматика, 2023
Objective: to study the pharmacokinetic parameters and safety of Dorsumio® (mirtazapine + tizanidine, extended-release tablets, 15 mg + 6 mg, JSC Valenta Pharm, Russia) taken once by healthy volunteers in comparison with Calixta®, a monocomponent drug ...
A. S. Goncharov, A. V. Grigoriev, A. A. Globenko, I. S. Goncharov, K. A. Muratov, D. V. Yaroshenko, A. A. Sidorova, A. V. Kapashin, O.  V. Kovchan, A. I. Bashkatova, M. A. Pasko   +10 more
doaj   +1 more source

Study on the accessibility and affordability of 50 drugs in Wuhan based on the WHO/HAI standardization method

Frontiers in Public Health, 2023
ObjectiveTo understand the availability and affordability of essential drugs in Wuhan since the implementation of the national essential medicine system, and to provide a basis for the subsequent formulation and improvement of related policies ...
Zuojun Dong, Shaoya Zhang, Shuaijun Wu, Xintong Xie, Guojun Sun, Xuanyao Yu   +5 more
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A COMPARATIVE STUDY OF EFFICACY AND TOLERABILITY OF ORIGINAL AND GENERIC SIMVASTATIN IN PATIENTS WITH HYPERLIPIDEMIA

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study efficacy and tolerability of original and generic simvastatin in patients with hyperlipidemia. Material and methods. Patients (6 men and 24 women) aged 38 to 77 years, which needed in lipid-lowering therapy were included into the open ...
V. P. Voronina, S. N. Tolpygina, N. P. Kutishenko, N. A. Dmitrieva, Yu. V. Lukina, S. Yu. Martsevich   +5 more
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Effective blood pressure reduction: results of the regional program “DOVERIE”

Российский кардиологический журнал, 2018
In clinical practice, quite often the practitioner faces difficulties in correcting arterial pressure in patients with arterial hypertension. Patients mostly for various reasons prefer to be treated with generic drugs, sometimes to the detriment of the ...
N. V. Dobryninа, S. S. Yakushin
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Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment–Drug Conjugates (FDCs)

Pharmaceutics, 2022
Antibody–drug conjugates (ADCs) derived from a full immunoglobulin-G (IgG) are associated with suboptimal solid-tumor penetration and Fc-mediated toxicities. Antibody fragment–drug conjugates (FDCs) could be an alternative.
Louis Jolivet, Imène Ait Mohamed Amar, Catherine Horiot, Fanny Boursin, Cyril Colas, Stéphanie Letast, Caroline Denevault-Sabourin, Emilie Allard-Vannier, Nicolas Joubert, Nicolas Aubrey   +9 more
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COMPARISON OF ANTIPLATELET EFFICACY OF ORIGINAL AND GENERIC ENTEROSOLUBLE ACETYLSALICYLIC ACID IN PATIENTS WITH HIGH CARDIOVASCULAR RISK. SIMPLE BLIND CROSSED RANDOMIZED CONTROLLED STUDY (IKAR)

Рациональная фармакотерапия в кардиологии, 2016
Aim. To compare the antiplatelet efficacy of the original and generic enterosoluble tableted acetylsalicylic acid (ASA) in patients with high cardiovascular risk.Material and мethods.
S. Yu. Martsevich, S. N. Tolpygina, E. S. Boychenko, R. E. Dubinskaya, Yu. V. Lukina, V. P. Voronina   +5 more
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THERAPEUTIC EQUIVALENCE OF ORIGINAL CLOPIDOGREL (PLAVIX) AND ITS GENERIC (EGITROMB). RESULTS OF COMPARATIVE RANDOMIZED CROSS-OVER BLIND STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study therapeutic equivalence (efficacy, safety and tolerability) of original clopidogrel (Plavix) and its generic (Egitromb) in patients of high cardiovascular risk. Material and methods.
V. V. Yakusevich, A. S. Petrochenko, V. A. Simonov, N. Yu. Levshin, A. D. Deev   +4 more
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On the debate of original drug versus generic drug

Psychiatry and Clinical Psychopharmacology, 2021
The original drugs are protected by the world's most powerful patent protection laws for a certain period of time and sonar equivalent (generic) drugs may be manifactured at the end of the patent protection period.
Mesut Çetin, Feyza Arıcıoğlu
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