Results 1 to 10 of about 1,506,160 (162)
Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions [PDF]
Journal of Pharmaceutical Health Care and Sciences, 2020 Background Generic drugs are heavily promoted in Japan. The aim of this retrospective single-center study was to clarify whether the frequency and reason that patients request a switch from a generic drug to the original drug differ according to ...
Yuhei Hamada +8 more
doaj +2 more sources
The Top-100 Highly Cited Original Articles on Drug Therapy for Ventilator-Associated Pneumonia
Frontiers in Pharmacology, 2019 Background: In recent decades, research on drug therapy for ventilator-associated pneumonia (VAP) remains one of the major hot-spots in the field of critical care medicine, but relevant data are not satisfactory.
Chao-Yang Wang +17 more
doaj +3 more sources
Comparative Study of Drug Efficacy and Drug Additives between Generic Drugs and Original Drugs
Yakugaku Zasshi, 2007 In the present study, we tested three kinds of sleeping drugs, consisting mainly of triazolam, brotizolam, and flunitrazepam, to compare the drug efficacy of generic drugs with that of original drugs. After these drugs were administered orally to mice, drug efficacy was evaluated in terms of ambulation, onset time of sleep, and duration of sleep in the
Hiromi, Katoh +2 more
exaly +4 more sources
The problem of choice: original drug or generic? Emphasis on rosuvastatin
Рациональная фармакотерапия в кардиологии, 2022 An increase in the life expectancy of the population and the number of polymorbid patients with a combination of two or more diseases in different age categories, including among young people, has led to a significant increase in the cost of medical care
O. A. Polyakova, O. D. Ostroumova
doaj +1 more source
Неврология, нейропсихиатрия, психосоматика, 2023 Objective: to study the pharmacokinetic parameters and safety of Dorsumio® (mirtazapine + tizanidine, extended-release tablets, 15 mg + 6 mg, JSC Valenta Pharm, Russia) taken once by healthy volunteers in comparison with Calixta®, a monocomponent drug ...
A. S. Goncharov +10 more
doaj +1 more source
Frontiers in Public Health, 2023 ObjectiveTo understand the availability and affordability of essential drugs in Wuhan since the implementation of the national essential medicine system, and to provide a basis for the subsequent formulation and improvement of related policies ...
Zuojun Dong +5 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study efficacy and tolerability of original and generic simvastatin in patients with hyperlipidemia. Material and methods. Patients (6 men and 24 women) aged 38 to 77 years, which needed in lipid-lowering therapy were included into the open ...
V. P. Voronina +5 more
doaj +1 more source
Pharmaceutics, 2022 Antibody–drug conjugates (ADCs) derived from a full immunoglobulin-G (IgG) are associated with suboptimal solid-tumor penetration and Fc-mediated toxicities. Antibody fragment–drug conjugates (FDCs) could be an alternative.
Louis Jolivet +9 more
doaj +1 more source
Effective blood pressure reduction: results of the regional program “DOVERIE”
Российский кардиологический журнал, 2018 In clinical practice, quite often the practitioner faces difficulties in correcting arterial pressure in patients with arterial hypertension. Patients mostly for various reasons prefer to be treated with generic drugs, sometimes to the detriment of the ...
N. V. Dobryninа, S. S. Yakushin
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To compare the antiplatelet efficacy of the original and generic enterosoluble tableted acetylsalicylic acid (ASA) in patients with high cardiovascular risk.Material and мethods.
S. Yu. Martsevich +5 more
doaj +1 more source