Results 81 to 90 of about 2,641,306 (328)

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

open access: yesAdvanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan   +24 more
wiley   +1 more source

Party system institutionalization and the quality of democracy in eastern Europe [PDF]

open access: yes, 2009
Almost two decades have passed since the Third Wave of democratization brought an avalanche of new, relatively unstable democracies into being in Eastern Europe.
Casal B\ue9rtoa, Fernando
core  

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

open access: yesAdvanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu   +8 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

open access: yesAdvanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang   +12 more
wiley   +1 more source

The Breakdown of the Spanish Two-Party System: The Upsurge of Podemos and Ciudadanos in the 2015 General Election

open access: yesCrisis Elections, New Contenders and Government Formation, 2016
The 2015 general election marked the end of the two-party system that had existed in Spain since the restoration of democracy. Two new parties, ‘Podemos’ and ‘Ciudadanos’, entered the national arena for the first time and together obtained 34.6 per cent ...
Lluís Orriols, Guillermo Cordero
semanticscholar   +1 more source

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

open access: yesAdvanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang   +5 more
wiley   +1 more source

Italy: from Tangentopoli to the new party system

open access: yesMiscelánea Comillas, 2017
Between 1992 and 1994 there was a change in Italian politics of extraordinary importance as a result of the numerous scandals of corruption, in a process that became known with the name of Tangentopoli.
Pablo Martín de Santa Olalla Saludes
doaj  

Stress, strain and stability in the French party system

open access: yesThe French party system, 2018
This chapter presents an overview of the evolution of the French party system in the first forty-five years of the Fifth Republic. During the Third and Fourth Republics, the fragmented structure of the party system, along with the parliamentary basis of ...
Alistair Cole
semanticscholar   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

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