Results 31 to 40 of about 173,109 (251)
EU Courts’ review of decisions imposing fines in EU state aids cases
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013 The aim of this article is to provide a comprehensive view on the application of the principle of proportionality in the Commission’s decisions imposing fines in the area of state aids as well as the EU courts exercise of the jurisdiction over these ...
Jana Mikušová
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Piecewise straightening and Lipschitz simplicial volume [PDF]
, 2015 We study the Lipschitz simplicial volume, which is a metric version of the simplicial volume. We introduce the piecewise straightening procedure for singular chains, which allows us to generalize the proportionality principle and the product inequality ...
Strzałkowski, Karol
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The principle of proportionality in the creation of administrative law [PDF]
, 2017 Przedmiotem opracowania jest charakterystyka zasady proporcjonalności (adekwatności celu i środka) w tworzeniu prawa administracyjnego. Autor opisuje zagadnienia związane z analizowaną zasadą, które winny być rozważane w procesie legislacji ...
Folak, Łukasz
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Plato on the Mechanics of Koinōnia Formation
Areté, 2022 This paper argues that, in order to understand the unified relations that are commonly predicated of koinōnia in the ethical, political, and cosmological spheres respectively, one must first appreciate certain prerequisite “principles” or “rules” that ...
Stephanos Stephanides
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Правоприменение, 2021 The subject of the research is the principle of proportionality as an intersectoral principle of legal responsibility. It has a constitutional nature and guarantees fairness in resolving the cases of constitutional responsibility. This principle provides
V. V. Ignatenko +2 more
doaj +1 more source
On the investment implications of bankruptcy laws [PDF]
, 2010 Axiomatic analysis of bankruptcy problems reveals three major principles: (i) proportionality (PRO), (ii) equal awards (EA), and (iii) equal losses (EL). However, most real life bankruptcy procedures implement only the proportionality principle.
Kıbrıs, Arzu +3 more
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