Results 121 to 130 of about 128,071,639 (264)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Environmental Restoration of Invaded Ecosystems: How Much Versus How Often? [PDF]
Replaced with revised version of paper 12/15/05.Environmental restoration, Resilience, Restoration failure, Invasive Species, Environmental Economics and Policy,
Ranjan, Ram
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 2019 Leading •Innovating Partnering UPPER MISSISSIPPI RIVER RESTORATION HABITAT REHABILITATION AND ENHANCEMENT PROJECT PLANNING AND DESIGN WORKSHOP May 6-8, 2019 AGENDA Pre-Workshop Webinars (April/May) Habitat Needs Assessment-II Upper Mississippi River ...
Upper Mississippi River Restoration Program (U.S.);
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Diacritic Restoration and the Development of a Part-of-Speech Tagset for the Māori Language [PDF]
, 2012 This thesis investigates two fundamental problems in natural language processing: diacritic restoration and part-of-speech tagging. Over the past three decades, statistical approaches to diacritic restoration and part-of-speech tagging have grown in ...
Cocks, John
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Overview of stream restoration technology: State of the science
ecosystem MANAGEMENT AND RESTORATION Technology News from the Ecosystem Management and Restoration Research Program October 1999 Overview of stream restoration technology: State of the science by J.
Engineer Research and Development Center (U.S.); Ecosystem Management and Restoration Research Program (U.S.);
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The efficacy of hazardous fuel treatments: A rapid assessment of the economic and ecologic consequences of alternative hazardous fuel treatments [PDF]
, 2013 Several persistent questions related to wildfire economics and fuel treatment effectiveness continue to concern federal budget analysts at the Office of Wildland Fire in the U.S. Department of Interior.
Ecological Restoration Institute
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
When large and severe disturbances affect mountain forests, their ability to provide fundamental ecosystem services may be impaired for a long time. Indeed, in the Alps, forested slopes exert a crucial protective function and rapidly restoring the forest
Emanuele Lingua +9 more
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